Author

R. B. Werder

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. A. Wilson· 2 shared D. N. Kotton· 2 shared A. Ali· 1 shared A. Bissell· 1 shared A. Cupic· 1 shared A. E. Goldfeld· 1 shared A. E. Tseng· 1 shared A. Fernandez-Sesma· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

A. A. Wilson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The maternal microbiome regulates infant respiratory disease susceptibility via intestinal Flt3L expression and plasmacytoid dendritic cell hematopoiesis

M. A. A. Sikder, R. B. Rashid, T. Ahmed, I. Sebina, D. R. Howard, M. A. Ullah, M. M. Rahman, J. P. Lynch, B. Curren, R. B. Werder, J. Simpson, A. Bissell, M. Morrison, C. Walpole, K. J. Radford, , S. Phipps

The paper shows that a maternal low-fibre diet disrupts infant immune development, increasing susceptibility to respiratory infections and asthma, and that propionate-producing bacteria can reverse this effect.

bioRxiv · Jan 5, 2023Immunology

The oral drug nitazoxanide restricts SARS-CoV-2 infection and attenuates disease pathogenesis in Syrian hamsters

L. Miorin, C. E. Mire, S. Ranjbar, A. J. Hume, J. Huang, N. A. Crossland, K. M. White, M. Laporte, T. Kehrer, V. Haridas, E. Moreno, A. Nambu, S. Jangra, A. Cupic, M. Dejosez, , A. E. Goldfeld

The paper shows that nitazoxanide inhibits SARS-CoV-2 replication and pathogenesis in human and hamster models, and synergizes with remdesivir against multiple variants.

bioRxiv · Feb 8, 2022 · PreprintImmunology

Modeling of Alpha-1 Antitrypsin Deficiency with Syngeneic Human iPSC-Hepatocytes Reveals Metabolic Dysregulation and Cellular Heterogeneity in PiMZ and PiZZ Hepatocytes

J. Kaserman, R. B. Werder, F. Wang, T. Matte, M. I. Higgins, M. Dodge, J. Lindstrom-Vautrin, A. Hinds, E. Bullitt, I. Caballero, X. Shi, R. E. Gerszten, N. Brunetti-Pierri, M. Liesa, C. Villacorta-Martin, , A. A. Wilson

This study uses CRISPR-Cas9 to create syngeneic iPSC-derived hepatocytes with ZAAT heterozygosity, revealing metabolic dysregulation and cellular heterogeneity in MZ and ZZ cells.

bioRxiv · Feb 1, 2022 · PreprintCell Biology