Author

R. Madansein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

K. Nargan· 2 shared A. A. Tu· 1 shared A. du Plessis· 1 shared A. G. White· 1 shared A. J. Steyn· 1 shared A. K. Shalek· 1 shared A. Leslie· 1 shared A. Myers· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

K. Nargan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells

A.-K. Reuschl, M. Shivkumar, D. Mesner, L. J. Pallett, J. A. Guerra-Assuncao, R. Madansein, K. J. Dullabh, A. Sigal, J. P. Thornhill, C. Herrera, S. Fidler, M. Noursadeghi, M. Maini, C. Jolly

This study shows HIV-1 infects resting memory T cells without prior activation, inducing a tissue-resident memory-like phenotype driven by Vpr.

bioRxiv · Jan 25, 2021Microbiology

Multimodal profiling of lung granulomas reveals cellular correlates of tuberculosis control

H. P. Gideon, T. K. Hughes, C. N. Tzouanas, M. H. Wadsworth, A. A. Tu, T. M. Gierahn, J. M. Peters, F. H. Hopkins, J.-R. Wei, C. Kummerlowe, N. L. Grant, K. Nargan, J. Phuah, H. J. Borish, P. Maiello, , A. K. Shalek

The paper identifies cellular and temporal factors associated with bacterial control in tuberculosis granulomas using multimodal data.

bioRxiv · Oct 24, 2020 · PreprintImmunology

3D microarchitecture of the human tuberculous granuloma

G. A. Wells, J. N. Glasgow, K. Nargan, K. Lumamba, R. Madansein, K. Maharaj, R. L. Hunter, T. Naidoo, P. Ramdial, L. Coetzer, S. le Roux, A. du Plessis, A. J. Steyn

This study uses 3D X-ray imaging to reveal complex, branched structures of human tuberculous granulomas, challenging the traditional view of spherical granulomas and suggesting implications for TB treatment strategies.

bioRxiv · Jun 14, 2020 · PreprintMicrobiology