R. Sullivan

Microglial NF-κB Signaling Deficiency Protects Against Metabolic Disruptions Caused by Volatile Organic Compound via Modulating the Hypothalamic Transcriptome

The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth

This study identifies LamH, a glycoside hydrolase that cleaves -1,6-mannoside linkages in LAM/LM, enabling their export to the capsule and promoting bacterial growth.

Molecular epidemiology of carbapenemase-producing Acinetobacter spp. from Israel, 2001-2006: earliest report of blaNDM predating the oldest known blaNDM-positive strains

This study identifies carbapenemase genes in Acinetobacter spp. from Israel between 2001-2006, finding the earliest reported blaNDM-1 in an A. junii isolate from 2004.

Altered interactions between circulating and tissue-resident CD8 T cells with the colonic mucosa define colitis associated with immune checkpoint inhibitors

This study identifies altered interactions between circulating and tissue-resident CD8 T cells with the colonic mucosa in immune checkpoint inhibitor-associated colitis using single-cell RNA sequencing and other multi-omics approaches.

Modelling bistable tumour population dynamics to design effective treatment strategies

This study models bistable tumour population dynamics to evaluate treatment strategies, finding that periodic treatments outperform static ones and optimal control theory-based treatments are most effective.

The Growth Hormone Secretagogue Receptor, Ghrelin and Biochemical Signaling Molecules in Human Heart Failure

The paper examines GHSR and ghrelin levels in cardiac tissue from transplant patients to assess their correlation with heart failure markers and function.