Author

Ross J. Lennen

University of Edinburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Maurits A. JanseniD· 3 shared Juraj Koudelka· 2 shared Karen J. HorsburghiD· 2 shared Nela FialovaiD· 2 shared Akihiro Kitamura· 1 shared Alessandra GranataiD· 1 shared Alexandra V. PokhilkoiD· 1 shared Anna WilliamsiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersNeuroscience

Maurits A. JansenORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pericyte Loss Reprogrammes Capillary Endothelium and Drives White Matter Injury in Small Vessel Disease

Dorota Stefancova, Audrey Chagnot, Michael D.E. Sewell, Nela Fialova, Conor McQuaid, Joseph O. Uweru, Solvig Becker, Marina Romero-Bernal, William Mungall, Vicky Walczak-Gillies, Tracy D. Farr, Ross J. Lennen, Maurits A. Jansen, Owen Dando, Justyna Cholewa-Waclaw, Axel Montagne

bioRxiv · May 13, 2026 · PreprintNeuroscience

Cerebral small vessel disease due to Col4a1 mutations include cognitive impairment and white matter defects that can be modulated by targeting protein folding.

Gaia Brezzo, Alexandra V. Pokhilko, Jon Moss, Juraj Koudelka, Maurits A. Jansen, Ross J. Lennen, Gerard Thompson, Nela Fialova, Sofia Marina Konstantinidou, Joyce L.W. Yau, Erin Boland, Anna Williams, Stuart McRae Allan, Alessandra Granata, Sanjay Sinha, , Karen J. Horsburgh

This study identifies cognitive impairment and white matter defects in a mouse model of cerebral small vessel disease caused by Col4a1 mutations and shows that targeting protein folding can alleviate these issues.

bioRxiv · Apr 4, 2025 · PreprintNeuroscience

Pulsation changes link to impaired glymphatic function in a mouse model of vascular cognitive impairment

Mosi Li, Akihiro Kitamura, Joshua Beverley, Juraj Koudelka, Jessica Duncombe, Ross J. Lennen, Maurits A. Jansen, Ian Marshall, Bettina Platt, Ulrich K. Wiegand, Roxana Octavia Carare, Raj N. Kalaria, Jeffrey J. Iliff, Karen J. Horsburgh

This study shows that bilateral common carotid stenosis impairs glymphatic function and vascular pulsation in mice, contributing to cognitive decline in vascular cognitive impairment.

Frontiers in Aging Neuroscience · Jan 13, 2022Peer-reviewedNeuroscience