Author

S. A. Shah

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 8 Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Assay:metagenomics· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Approach:statistical model· 4 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

H. Bisgaard· 4 shared J. Russel· 4 shared J. Stokholm· 4 shared J. Thorsen· 4 shared S. J. Sorensen· 4 shared D. S. Nielsen· 3 shared G. A. Vestergaard· 3 shared L. Deng· 3 shared

Activity by Year

2019-2023 · peak 6/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersMicrobiology

H. Bisgaard

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

The influence of early life exposures on the infant gut virome

Y. Zhang, J. L. Castro-Mejia, L. Deng, S. A. Shah, J. Thorsen, C. L. Rodriguez, L. E. Jessen, M. B. Dion, B. Chawes, K. Bonnelykke, S. J. Sorensen, H. Bisgaard, S. Moineau, M.-A. Petit, J. Stokholm, D. S. Nielsen

This study investigates how early life factors influence the gut virome composition in infants, identifying environmental exposures that shape viral communities and their potential metabolic impacts.

bioRxiv · Mar 5, 2023Microbiology

Co-localization of antibiotic resistance genes is widespread in the infant gut microbiome and associates with an immature gut microbial composition

X. Li, A. Brejnrod, U. Trivedi, J. Russel, J. Thorsen, S. A. Shah, G. A. Vestergaard, M. A. Rasmussen, J. Nesme, H. Bisgaard, J. Stokholm, S. J. Sorensen

This study finds that antibiotic resistance gene co-localization is common in infants' gut microbiomes and linked to immature microbial composition.

bioRxiv · Feb 19, 2023Microbiology

Phytochemical and antibacterial analyses of Onychium japonicum (Thunb.) Kunze.

S. A. Shah, G. M. Shah, M. M. Hassan, W. F. Alsanie, S. Nawazish, W. Ali, A. Basit, D. N. Shafqath, N. Jabeen, S. A. M. Shah, Z. Shah, M. Ishtiaq, D. A. GUL, j. alam, M. ISLAM, , Experts from Microbiology and Biichemistry as well participated in the current work

This study investigates the phytochemical composition and antibacterial potential of Onychium japonicum, finding it rich in bioactive compounds and active against multidrug-resistant bacteria.

bioRxiv · Jun 14, 2022 · PreprintMicrobiology

A short prokaryotic argonaute cooperates with membrane effector to confer antiviral defense

Z. Zeng, Y. Chen, R. Pinilla-Redondo, S. A. Shah, F. Zhao, C. Wang, Z. Hu, C. Zhang, R. Whitaker, Q. She, W. Han

The paper identifies a short prokaryotic argonaute (pAgo) in Sulfolobus islandicus that, along with Aga1 and Aga2, provides antiviral defense through abortive infection.

bioRxiv · Dec 9, 2021 · PreprintMicrobiology

UG/Abi: a highly diverse family of prokaryotic reverse transcriptases associated with defense functions

M. R. Mestre, L. Gao, S. A. Shah, A. Lopez-Beltran, A. Gonzalez-Delgado, F. Martinez-Abarca, J. Iranzo, M. Redrejo-Rodriguez, F. Zhang, N. Toro

The paper systematically analyzes UG and Abi RTs, classifies them into three major classes, and demonstrates their association with defense functions and antiphage roles.

bioRxiv · Dec 2, 2021Evolutionary Biology

Hundreds of viral families in the healthy infant gut

S. A. Shah, L. Deng, J. Thorsen, A. G. Pedersen, M. B. Dion, J. Castro Mejia, R. Silins, F. O. Romme, R. Sausset, E. O. Ndela, M. H. Hjemso, M. A. Rasmussen, T. Redgwell, G. A. Vestergaard, Y. Zhang, , D. S. Nielsen

This study manually resolves viral dark matter in a large infant gut virome dataset, identifying over ten thousand viral species across 248 families and expanding bacteriophage taxonomy.

bioRxiv · Jul 2, 2021 · PreprintMicrobiology

Prophages in the infant gut are largely induced, and may be functionally relevant to their hosts.

T. A. Redgwell, J. Thorsen, M.-A. Petit, L. Deng, G. A. Vestergaard, J. Russel, H. Bisgaard, D. S. Nielsen, S. J. Sorensen, J. Stokholm, S. A. Shah

This study identifies prophages in infant gut metagenomes, showing they are largely induced and may influence microbiome dynamics through functional elements.

bioRxiv · Jun 25, 2021 · PreprintMicrobiology

CRISPR-Cas systems are widespread accessory elements across bacterial and archaeal plasmids

R. Pinilla-Redondo, J. Russel, D. Mayo-Munoz, S. A. Shah, R. A. Garrett, J. Nesme, J. S. Madsen, P. C. Fineran, S. J. Soerensen

The paper investigates CRISPR-Cas systems on bacterial and archaeal plasmids, finding they are widespread, diverse, and involved in plasmid-plasmid conflicts.

bioRxiv · Jun 4, 2021Microbiology

Endothelial Pannexin 1-TRPV4 channel signaling lowers pulmonary arterial pressure

Z. Daneva, M. Ottolini, Y. L. Chen, E. Klimentova, S. A. Shah, R. D. Minshall, C. I. Seye, V. E. Laubach, B. E. Isakson, S. K. Sonkusare

The paper shows endothelial Panx1-TRPV4 signaling via ATP and P2Y2R lowers pulmonary arterial pressure by reducing contractility.

bioRxiv · Mar 9, 2021Biochemistry

Type IV CRISPR-Cas systems are highly diverse and involved in competition between plasmids

R. Pinilla-Redondo, D. Mayo-Munoz, J. Russel, R. A. Garrett, L. Randau, S. J. Soerensen, S. A. Shah

This study identifies a diverse range of type IV CRISPR-Cas systems primarily found on plasmids, revealing their role in plasmid competition and cross-talk with type I systems.

bioRxiv · Sep 24, 2019Microbiology