Author

S. Nam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

O. Chaudhuri· 2 shared A. A. Dominguez· 1 shared A. C. Martin· 1 shared B. E. Kang· 1 shared C.-W. Lee· 1 shared D. Kim· 1 shared D. L. Keatinge-Clay· 1 shared D. Ryu· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersCell Biology

O. Chaudhuri

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Loss-of-SIRT7 sensitizes hepatocellular carcinoma to sorafenib through the regulation of ERK Phosphorylation

Y. Kim, K.-Y. Jung, Y. H. Kim, P. Xu, Y. Jo, B. E. Kang, N. Pandit, J. Kwon, K. Gariani, J. Gariani, J. Lee, J. Verbeek, S. Nam, S.-J. Bae, K.-T. Ha, , J. Auwerx

This study shows that SIRT7 contributes to sorafenib resistance in HCC by enhancing ERK phosphorylation, and inhibiting SIRT7 with sorafenib reduces tumor growth.

bioRxiv · Mar 13, 2023 · PreprintCancer Biology

Central tolerance is impaired in the middle-aged thymic environment

J. N. Lancaster, D. L. Keatinge-Clay, J. Srinivasan, Y. Li, H. J. Selden, S. Nam, E. R. Richie, L. I. R. Ehrlich

This study shows that the middle-aged thymic environment impairs central tolerance by reducing mTECs and antigen-presenting cells, leading to less efficient negative selection and Treg induction.

bioRxiv · Jan 17, 2022Immunology

The nature of mitotic forces in epithelial monolayers

V. K. Gupta, S. Nam, J. Camuglia, J. L. Martin, E. N. Sanders, L. E. O'Brien, A. C. Martin, T. Kim, O. Chaudhuri

This study identifies two distinct stages of mitotic force generation in epithelial monolayers: protrusive forces driving mitotic elongation and outward forces facilitating post-mitotic re-spreading.

bioRxiv · Nov 16, 2020Cell Biology

YAP-independent mechanotransduction drives breast cancer progression

J. Y. Lee, J. Chang, A. A. Dominguez, S. Nam, J. Chang, H.-p. Lee, S. Varma, L. S. Qi, R. B. West, O. Chaudhuri

This study shows that mechanotransduction in breast cancer occurs without YAP, due to compact nuclear morphologies in vivo.

bioRxiv · Dec 13, 2018Cancer Biology