Author

S. R. Shaikh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Physiology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. E. Al-Shaer· 2 shared A. R. Verkerke· 2 shared J. A. Maschek· 2 shared J. E. Cox· 2 shared J. M. Johnson· 2 shared K. Funai· 2 shared P. D. Neufer· 2 shared P. J. Ferrara· 2 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. E. Al-Shaer

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Metabolic and functional impairment of CD8+ T cells from the lungs of influenza-infected obese mice

W. D. Green, A. E. Al-Shaer, Q. Shi, N. J. MacIver, M. A. Beck, S. R. Shaikh

This study shows that diet-induced obesity impairs pulmonary CD8+ T cell metabolism and function during influenza infection, leading to reduced effector cells and cytokine production.

bioRxiv · Apr 19, 2020Immunology

Resolvin E1 derived from eicosapentaenoic acid prevents hyperinsulinemia and hyperglycemia in a host genetic manner

A. Pal, A. E. Al-Shaer, W. Guesdon, M. J. Torres, M. Armstrong, K. Quinn, T. Davis, N. Reisdorph, P. D. Neufer, E. E. Spangenburg, I. Carroll, R. P. Bazinet, G. V. Halade, J. Claria, S. R. Shaikh

This study shows EPA prevents hyperinsulinemia and hyperglycemia via RvE1, which acts through ERV1/ChemR23, and highlights host genetic variation in metabolic responses.

bioRxiv · Mar 31, 2020Biochemistry

The Lands cycle modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle

P. J. Ferrara, X. Rong, J. A. Maschek, A. R. Verkerke, P. Siripoksup, H. Song, K. C. Krishnan, J. M. Johnson, J. Turk, J. A. Houmard, A. J. Lusis, J. E. Cox, S. R. Shaikh, P. Tontonoz, K. Funai

The study identifies LPCAT3 as a key regulator of plasma membrane lipid organization and insulin sensitivity in skeletal muscle, showing its role in modulating lipid metabolism and insulin action.

bioRxiv · Dec 23, 2019 · PreprintPhysiology

Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity

T. D. Heden, J. M. Johnson, P. J. Ferrara, H. Eshima, A. R. Verkerke, E. J. Wentzler, P. Siripoksup, T. M. Narowski, C. B. Coleman, C.-T. Lin, T. E. Ryan, P. T. Reidy, L. E. de Castro Bras, C. M. Karner, C. F. Burant, , K. Funai

The paper shows that mitochondrial phospholipids, specifically phosphatidylethanolamine (PE), regulate respiratory capacity in skeletal muscle, with PE deficiency causing respiratory failure and oxidative stress.

bioRxiv · Apr 9, 2019Physiology