S. Sathe

Chimera alert! The threat of chimeric sequences causing inaccurate taxonomic classification of phytoplasma strains

This study identifies chimeric 16S rRNA gene sequences in phytoplasma strains using ChimeraSlayer and UCHIME, highlighting their threat to accurate taxonomic classification.

Comparison of heat-inactivated and infectious SARS-CoV-2 across indoor surface materials shows comparable RT-qPCR viral signal intensity and persistence

This study compares RT-qPCR signal intensity and persistence of heat-inactivated and infectious SARS-CoV-2 on different surfaces, showing similar decay patterns and enabling simplified environmental monitoring protocols.

Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies

This study investigates how RBM20 mutations affect splicing and ribonucleoprotein granules in cardiomyopathy, revealing distinct pathogenic mechanisms between missense and knockout mutations.

Antagonistic interactions subdue inter-species green-beard cooperation in bacteria.

The paper shows that inter-species green-beard cooperation in bacteria is undermined by antagonistic interactions, as Pseudomonas aeruginosa outcompetes Burkholderia cenocepacia despite shared cooperative traits.

Novel engraftment and T cell differentiation of human hematopoietic cells in Art-/- IL2RG-/ SCID pigs

The paper generates a T-B-NK-SCID pig model via CRISPR/Cas9 and demonstrates successful human hematopoietic cell engraftment in blood and lymphoid organs after in utero injection.

Genetic architecture constrains exploitation of siderophore cooperation in Burkholderia cenocepacia

This study shows that genetic linkage prevents cheating in siderophore cooperation in Burkholderia cenocepacia by linking synthesis and receptor genes, and demonstrates that breaking this linkage allows cheaters to exploit the public good.