S. Shin

This study identifies a neonatal liver niche that promotes hepatoblastoma metastasis via the Cxcl1/Cxcr2 axis, showing increased tumor aggressiveness and hypoxia in early postnatal models.

This study shows that V. fischeri alters its swimming behavior in confined spaces, escaping through reduced directional fluctuation and a refractory period between reversals.

This study shows that human NAIP/NLRC4 and NLRP3 inflammasomes detect Salmonella T3SS components, restricting bacterial replication in macrophages.

This study shows that an AS03-adjuvanted SARS-CoV-2 spike protein vaccine induces strong antibody responses and protects nonhuman primates from viral challenge.

The paper shows red blood cells detect and bind DNA, triggering immune responses during infections.

This study evaluates adjuvants for a subunit SARS-CoV-2 nanoparticle vaccine in non-human primates, showing durable neutralizing antibody responses and protection against infection.

This paper introduces a deep learning and optimization framework to estimate lower extremity joint angles from inertial data without magnetometer reliance, achieving sub-3 degree RMS error in motion trials.

The paper identifies a new pancreatic cancer subtype with low protein synthesis but high integrated stress response activation, linked to metabolic impairments and drug resistance.

This study uses transcriptomic data to resolve the phylogenetic relationships within Antliophora, finding fleas are sister to either a monophyletic Mecoptera or arose within mecopteran families, potentially making Mecoptera paraphyletic.

This paper introduces a label-free volumetric imaging technique for thick-tissue slides with subcellular resolution, demonstrating its ability to visualize various tumor types and pathologies.

This study shows human GBP1 promotes L. pneumophila vacuole rupture and inflammasome activation, differing from mouse GBPs which are dispensable for vacuole rupture.

Infected macrophages use alveolar epithelium to reprogram bystander myeloid cells via IL-1 and GM-CSF, enhancing antibacterial inflammation.

This study uses single-molecule techniques to show that yeast CHD1 remodels nucleosomes through unique DNA unwrapping and translocation dynamics involving ATP binding and hydrolysis.

This study investigates the structural dynamics of the LOV2 domain in AsLOV2, showing that Q513 and N414 mediate J-helix unfolding linked to optogenetic function.

This study measures 3-D morphology changes in human red blood cells under localized photothermal effects using gold nanorods and 3D quantitative phase imaging.

This study identifies NSUN2 as a methyltransferase introducing 5-methylcytosine in mitochondrial tRNAs and shows its necessity for m5C modification but not for tRNA stability or oxidative phosphorylation in differentiated cells.

This study demonstrates that an implantable electrical stimulation bioreactor with liquid crystal polymer electrodes enhances bone regeneration in rabbit mandibular defects compared to a sham control and rhBMP-2 treatment.

This study identifies adaptive gene family expansions in polyphagan beetles associated with their shift to plant-feeding, supporting the role of plant chemical defenses in beetle diversification.

This paper quantifies lipid content in individual microalgal cells using refractive index tomography without chemical extraction.

The paper visualizes and quantifies microfluidic mixing using quantitative phase imaging without exogenous labels, validated against Fick's law calculations.