S. Zhou

This study demonstrates that operational tolerance can be achieved and maintained in half-size liver allografts through bone marrow stem cell repopulation and short-term immunosuppression, leading to long-term graft survival without rejection.

This study examines structural and biochemical features of Delta and Kappa SARS-CoV-2 variants, showing increased ACE2 binding and antibody escape, contributing to Delta's dominance.

The paper identifies piperlongumine as a covalent E3 ligase recruiter that, when conjugated with CDK9 inhibitors, induces targeted protein degradation of CDK9 and EML4-ALK fusion oncoprotein.

This study evaluates the anti-tumor activities of 25 sulfonylurea derivatives in breast carcinoma cell lines, finding concentration- and time-dependent inhibitory effects on cell growth, proliferation, migration, and survival.

This study identifies a broadly neutralizing antibody fragment and analyzes spike protein mutations in SARS-CoV-2 variants to understand their structural and functional impacts on antibody evasion.

The paper analyzes mutations in the SARS-CoV-2 receptor binding domain to understand their effects on ACE2 and antibody binding in variants of concern.

The paper introduces a robust beta regression method for dose-response curve estimation and develops a web tool for its implementation.

This study examines how habitat and phylogeny shape gut microbiomes in Sinocyclocheilus cavefish, finding habitat is the main driver, with captivity homogenizing microbiomes across species.

This study identifies LRRC23 as a conserved component of the radial spoke complex in mouse sperm, essential for flagellar motility and male fertility but not ciliary function.

This study characterizes the gut and skin microbiomes of Ichthyophis bannanicus larvae and compares them to other amphibian orders, finding distinct microbial communities with limited gut-skin overlap.

This study identifies H2B.8 as a histone variant that mediates chromatin condensation in flowering plant sperm through phase separation, enabling nuclear compaction without transcriptional inhibition.

This study shows that AAV6 and AAV9 vaccines induce cellular immunity protecting mice from SARS-CoV-2 pneumonia without relying on neutralizing antibodies.

The paper creates an isogenic cell line panel for drug screening, finding that most lines did not fully inactivate genes but a subset had biallelic disruptions, enabling drug response testing.

The paper reports the structures of M. tuberculosis cytochrome bcc complexed with two anti-TB drugs, revealing binding sites and interactions that inform inhibitor design.

This study identifies a maize inbred line, Xi502, that mounts effective defense against fall armyworm, showing distinct transcriptomic and elicitation responses compared to the susceptible line B73.

The paper shows that environmental selection overrides the distance-decay pattern in soil prokaryotic communities across biomes, revealing a U-shape pattern due to homogeneous environmental factors.

The paper studies a rare bamboo rhizome phenomenon with excessive shoots, analyzing its associated microbiome and finding correlations between bacterial genera and shoot numbers.

The paper presents cryo-EM structures of the N501Y SARS-CoV-2 spike protein complex with ACE2 and neutralizing antibodies, showing increased ACE2 binding affinity and retained epitopes.

The paper shows that structural variants causing cis-regulatory element hijacking have a greater impact on gene expression than changes in three-dimensional chromatin topology in primary prostate cancer.

This paper introduces a trait-based optimality theory that unifies stomatal responses and plant biochemical acclimation, validated with experimental data from 18 species.

This paper introduces TASEC, a method that enhances protein labeling and detection by using split enzyme complementation with orthogonal tags, demonstrating applications in cell enrichment and interaction studies.

The paper withdraws due to potential data analysis artefacts affecting conclusions about functional structure and ecosystem multifunctionality.

The paper improves split fluorescent protein systems for better complementation efficiency and signal amplification in mammalian cells.

The paper generates a HEK-293T cell line expressing murine GM-CSF and shows it supports dendritic cell and alveolar macrophage differentiation as an alternative to commercial GM-CSF.

This study examines HIV-1 compartmentalization in semen of men with and without STI-associated urethritis, finding stable viral populations and limited replication despite STI treatment.

This study determines the structural basis for hormone-controlled antibiotic production in Actinobacteria by solving the X-ray structure of an MmfR-AHFCA complex and elucidating DNA release mechanisms.

This study demonstrates that the antiviral NHC/EIDD-2801 inhibits SARS-CoV-2 and multiple coronaviruses, showing therapeutic efficacy and oral bioavailability in mice.

This study identifies the COMPASS-like complex in M. oryzae and shows it regulates H3K4me3-mediated gene expression critical for fungal development and pathogenesis.

This study shows that CTP synthase forms cytoophidia in archaea, extending the known presence of these structures to all three domains of life.