Author

T. Dandekar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Immunology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

L. Chunguang· 2 shared A. Altendorf-Hofmann· 1 shared A. Durotin· 1 shared A. J. Rutkowski· 1 shared A. L'Hernault· 1 shared A. Marchetto· 1 shared A. W. Whisnant· 1 shared A.-C. Winkler· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersMicrobiology

L. Chunguang

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Soluble VE-cadherin disrupts endothelial barrier function via VE-PTP/RhoA signalling

J.-L. Knop, N. Burkard, M. Danesh, T. Dandekar, M. Srivastava, M. Hiermaier, J. Waschke, S. Flemming, N. Schlegel

This study shows that soluble VE-cadherin fragments disrupt endothelial barrier function by interfering with VE-PTP/RhoA signaling in both in vitro and in vivo models.

bioRxiv · Oct 17, 2022 · PreprintPhysiology

The β-cell primary cilium is an autonomous Ca2+ compartment for paracrine GABA signalling

G. Sanchez, T. C. Incedal, J. P. Salcedo, P. O'Callaghan, S. Echeverry, P. M. Nguyen, B. Xie, S. Barg, J. Kreuger, T. Dandekar, O. Idevall-Hagren

The paper investigates Ca2+ dynamics in β-cell primary cilia and identifies GABA-B1 receptor-mediated paracrine signaling as a localized Ca2+ signaling mechanism.

bioRxiv · Aug 16, 2021Cell Biology

Antibody ligation of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), CEACAM3, and CEACAM6, differentially enhance the cytokine release of human neutrophils in responses to Candida albicans

E. Klaile, J. P. Prada Salcedo, T. E. Klassert, M. Besemer, A.-K. Bothe, A. Durotin, M. M. Mueller, V. Schmitt, C. H. Luther, M. Dittrich, B. B. Singer, T. Dandekar, H. Slevogt

bioRxiv · Feb 11, 2021 · PreprintImmunology

Intracellular Staphylococcus aureus perturbs the host cell Ca2+-homeostasis to promote cell death

K. Stelzner, A.-C. Winkler, L. Chunguang, C. P. Ade, T. Dandekar, M. Fraunholz, T. Rudel

This study identifies the calcium signaling pathway as critical for Staphylococcus aureus-induced host cell death through cytosolic and mitochondrial calcium overload.

bioRxiv · Aug 20, 2020Microbiology

Integrative functional genomics decodes herpes simplex virus 1

A. W. Whisnant, C. S. Juerges, T. Hennig, E. Wyler, B. Prusty, A. J. Rutkowski, A. L'Hernault, M. Goebel, K. Doering, J. Menegatti, R. Antrobus, N. J. Matheson, F. W. Kuenzig, G. Mastrobuoni, C. Bielow, , L. Doelken

This study decodes the complete HSV-1 transcriptome and translatome during lytic infection, identifying novel transcripts, ORFs, and regulatory elements.

bioRxiv · Apr 9, 2019Microbiology

Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma

M. F. Orth, J. S. Gerke, T. Knosel, A. Altendorf-Hofmann, J. Musa, R. Alba Rubio, S. Stein, M. Dallmayer, M. C. Baldauf, A. Marchetto, G. Sannino, S. Ohmura, J. Li, M. Hakozaki, T. Kirchner, , T. G. P. Grunewald

This study identifies AMPD2 as a prognostic biomarker for undifferentiated pleomorphic sarcoma using transcriptome analysis, immunohistochemistry, and functional assays.

bioRxiv · Mar 31, 2018Pathology