T. Huang

The paper shows STAT3 localizes in mitochondria-associated ER membranes, not mitochondria, and other mitochondrial TFs also localize to MAMs.

This study shows that BMI1 and RNF2 suppress transcription-replication conflicts and CFS instability by regulating RNA Pol II elongation and fork protection.

The paper uses single-cell RNA sequencing to identify distinct cellular responses to EWSR1-FLI1 down-regulation in Ewing sarcoma, revealing dormancy and stem-like features associated with drug resistance.

The paper uses single-cell RNA-seq to analyze human Wharton’s Jelly-derived MSCs, identifying heterogeneity in gene expression and potential marker genes for potency.

This study shows mast cells contribute to fibrosis and effector cell recruitment in dermal chronic GVHD, suggesting they are potential therapeutic targets.

This study identifies a Clostridia-rich microbiota as a contributor to excessive bile acid excretion in IBS-D patients through metagenomic and metabolomic analyses.

This study uses single-particle tracking to show that KRas diffusion and trafficking are regulated by nested membrane nanodomains in U2OS cells.

This study investigates the effects of fasting caecotrophy on growth performance and lipid metabolism in rabbits using RNA-Seq, finding reduced body weight, lipid droplet accumulation, and altered gene expression related to lipid metabolism.

The paper describes a high-throughput assay using Saccharomyces cerevisiae to assess sphingolipid kinase inhibitors and validates it with recombinant enzymes.