T. Sun

This study identifies prognostic non-tumor cell types in glioblastoma by analyzing gene expression across four cohorts, revealing risk and protective factors associated with immune response clusters.

This paper shows that combining ultrasound with an antibody improves Aβ removal and memory in Alzheimer's mice without causing brain bleeding.

This study shows that TIR signaling is essential for enhancing plant defense during pattern-triggered immunity by activating defense genes and increasing resistance to pathogens.

This study introduces a multi-enzyme directed evolution model to improve screening throughput and efficiency, revealing convergent evolution in two cytochrome P450 enzymes with distinct active sites achieving similar functions.

The paper identifies four linear B-cell epitopes on the SARS-CoV-2 spike protein that can elicit neutralizing antibodies in multiple species.

This study identifies B- and T-cell epitopes from SARS-CoV-2 surface glycoprotein using immune-informatics approaches, confirming their antigenicity and compatibility with HLA alleles for potential vaccine development.

The paper shows that pyrogenic carbon from fires reduces methane production in peatlands, leading to a net climate benefit by decreasing greenhouse gas emissions.

This study shows that inhibiting xCT/SLC7A11 induces ferroptosis in myofibroblastic hepatic stellate cells, reducing liver fibrosis without worsening liver injury.

This study identifies RIPK3 upregulation in recurrent breast tumors, showing it promotes proliferation but also creates dependence on cystine, offering new therapeutic targets.

This study uses multiscale simulations to model DNA phase separation induced by CoHex3+, showing aggregation into hexagonally ordered phases and toroid or fibre formation.

This study shows that in utero Lymphotoxin-beta receptor signaling programs mesenteric lymph node stromal cells to support adult IgA responses by influencing antibody class switch and IgA+ cell generation.

This study shows low-dose IFN-γ promotes tumor stemness in NSCLC via ICAM1-PI3K-Akt-Notch1 pathway, while high-dose IFN-γ induces apoptosis through JAK1-STAT1-caspase pathway.

This study shows TP, activated by Twist1, promotes HCC metastasis and VM via pentose Warburg effect by linking pentose phosphate pathway and glycolysis.

This study identifies MESH1 as a cytosolic NADPH phosphatase that promotes cell survival under ferroptosis by maintaining NADPH levels and induces transcriptional changes resembling bacterial stringent response.