Author

Vincent Hou

Karolinska University Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Molecular Biology· 2 Bioengineering· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:non-human primate· 1

Frequent Co-Authors

Samir EL AndaloussiiD· 4 shared Xiuming LiangiD· 4 shared André GörgensiD· 3 shared Doste Rashid MamandiD· 3 shared Joel Z. NordiniD· 3 shared Oscar P. B. WiklanderiD· 3 shared Dhanu GuptaiD· 2 shared Houze ZhouiD· 2 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMolecular Biology

Samir EL AndaloussiORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Bioengineered extracellular vesicles mitigate neuroinflammation by neutralizing pneumolysin and delaying disease onset in experimental pneumococcal meningitis

Kristine Farmen, Doste Rashid Mamand, Miguel Tofiño-Vian, Georgia Yfanti, Xiuming Liang, Vicky W.Q. Hou, Vincent Hou, Samir EL Andaloussi, Oscar P. B. Wiklander, Federico Iovino

This study develops bioengineered extracellular vesicles that neutralize pneumolysin and reduce inflammation in pneumococcal meningitis, improving survival in a mouse model.

Journal of Extracellular Vesicles · Sep 1, 2026Peer-reviewedNeuroscience

Efficient genome editing in the non-human primate brain using programmable extracellular vesicles

Xiuming Liang, Houze Zhou, Zubair Ahmed Nizamudeen, Eleni Kyriakopoulou, Angharad E. Evans, Samantha Roudi, Hernando Yesid Estupiñan, Julia Rädler, Vincent Hou, Callum D.W. Daniel, Inés Hernández-Pérez, Malika Singh, Pardis Parsi, Daniel A. Lonergan, Lidia Menéndez Berlana, , Samir EL Andaloussi

This paper demonstrates efficient genome editing in non-human primate brains using engineered extracellular vesicles, achieving therapeutic potential for neurological disorders.

bioRxiv · Aug 6, 2026 · PreprintMolecular Biology

Evaluation of Tetraspanins in Extracellular Vesicle Bioengineering

Doste Rashid Mamand, Oskar Gustafsson, Helena Sork, Rim Jawad Wiklander, Safa Bazaz, Xiuming Liang, Vincent Hou, Taavi Lehto, Dhanu Gupta, André Görgens, Joel Z. Nordin, Samir EL Andaloussi, Oscar P. B. Wiklander

This study investigates the role of tetraspanins in EV bioengineering by knocking out CD9, CD63, and CD81 in HEK293T cells and shows increased engineered EV production upon reintroduction of tetraspanin-fusion constructs.

Small Science · Mar 1, 2026Peer-reviewedBioengineering

Efficient delivery of gene editors using intein-engineered virus-like particles

Guannan Zhou, Vincent Hou, Houze Zhou, Samantha Roudi, Juliette Suermondt, Oskar Gustafsson, Zheyu Niu, Doste Rashid Mamand, Lien Van Hoecke, Oscar P. B. Wiklander, Roosmarijn E. Vandenbroucke, Joel Z. Nordin, André Görgens, Samir EL Andaloussi, Xiuming Liang

This paper develops intein-engineered virus-like particles for efficient gene editing delivery, achieving robust gene editing in multiple cell types and organs.

bioRxiv · Jan 26, 2026 · PreprintMolecular Biology