Author

W. M. Laprade

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

C. A. Dawson· 2 shared E. Crittenden· 2 shared J. M. Gutierrez· 2 shared K. E. Bartlett· 2 shared N. R. Casewell· 2 shared S. R. Hall· 2 shared T. P. Jenkins· 2 shared A. H. Laustsen· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersPharmacology & Toxicology

C. A. Dawson

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Author profile →

2 papers

Recent·Most cited

Dermonecrosis caused by spitting cobra snakebite results from toxin potentiation and is prevented by the repurposed drug varespladib

K. E. Bartlett, S. R. Hall, S. A. Rasmussen, E. Crittenden, C. A. Dawson, L.-O. Albulescu, W. M. Laprade, R. A. Harrison, A. J. Saviola, C. M. Modahl, T. P. Jenkins, M. C. Wilkinson, J. M. Gutierrez, N. R. Casewell

This study identifies toxin synergism in spitting cobra venom causing dermonecrosis and shows that varespladib prevents tissue damage in mouse models.

bioRxiv · Jul 20, 2023Pharmacology & Toxicology

Machine-learning guided Venom Induced Dermonecrosis Analysis tooL: VIDAL

W. M. Laprade, K. E. Bartlett, C. R. Christensen, T. D. Kazandjian, R. N. Patel, E. Crittenden, C. A. Dawson, M. Mansourvar, D. S. Wolff, T. J. Fryer, A. H. Laustsen, N. R. Casewell, J. M. Gutierrez, S. R. Hall, T. P. Jenkins

VIDAL is a machine-learning tool that automatically analyzes dermonecrosis in mouse models to assess antivenom efficacy, offering an accurate and reproducible alternative to manual methods.

bioRxiv · May 21, 2023Pharmacology & Toxicology