X. Huang

The paper identifies IL-24 as an anti-apoptotic factor in liver ER stress, showing its role in preventing cell death and its clinical relevance in acute liver failure.

This study develops the first low nanomolar LRH-1 agonist using structure-guided design, showing increased potency and anti-inflammatory effects in an organoid model.

This study identifies ZagA, a zinc metallochaperone in Bacillus subtilis, which interacts with FolE to sustain folate synthesis under zinc limitation, activated by the alarmone ZTP.

This study identifies and genotypes Trichosporon species isolated from giant pandas, finding 11 species with varying pathogenicity and genotypes.

This study investigates EAD properties in ventricular myocyte models, finding discrepancies between model predictions and experimental observations, particularly in inter-EAD intervals.

The paper introduces an open-source software tool for automated tracking of biopolymer networks in 2D and 3D using stretching open active contours, demonstrating its application in live cell studies.

The paper develops a platform to infer and validate signaling interactions at cellular resolution during C. elegans embryogenesis, identifying Notch interactions and their role in breaking fate symmetry.

This study identifies AMPKi as a compound that blocks 14-3-3 binding to CRAF, overcoming RAF inhibitor resistance by preventing paradoxical CRAF activation in cancer cells.