Y. Li

The paper investigates the regulatory role of MoISW2 in Magnaporthe oryzae, showing its impact on gene expression variability and niche-determinant genes, with implications for fungal evolution.

This study investigates DNA methylation inheritance in Pacific oysters, finding that half of parental methylation differences are passed to offspring and revealing sex-specific methylation patterns linked to Rho signaling.

This paper develops a chimpanzee adenovirus-based vaccine against the SARS-CoV-2 Delta variant and shows it induces strong immunity and protects mice from challenge.

This study identifies tomato SDG33 and SDG34 histone methyltransferases that regulate stress tolerance by modifying H3K4 and H3K36 methylation and expression of negative regulators.

This study predicts water deer range expansion and dispersal routes in Northeast Asia using MaxEnt and circuitscape, identifying key habitats and potential conservation corridors.

The paper develops a pipeline to measure exchange rates and concentrations of amide and arginine guanidinium protons in the mouse brain using CEST and validates it with specific mouse models.

This study shows Arid5a promotes IL-17-dependent autoimmunity but not antifungal immunity, suggesting targeted therapy could reduce autoimmune side effects.

This study shows that targeting OLIG2 with CT-179 reduces recurrence in SHH medulloblastoma models and improves survival when combined with radiotherapy.

This study identifies OsIRO3 as a negative regulator of Fe homeostasis in rice by repressing OsIRO2, a positive regulator of Fe uptake.

The paper identifies Flaviviridae-derived endogenous viral elements in shrew genomes, revealing an ancient origin of pestiviruses and their potential role as natural reservoirs.

This paper develops lyophilized mRNA-lipid nanoparticle vaccines that maintain stability at room temperature and show high antigenicity against SARS-CoV-2 variants in preclinical and human trials.

This study examines reassortment dynamics of influenza A virus in guinea pigs, ferrets, and swine, finding reassortment is common but more frequent in ferrets and guinea pigs than swine, with spatial compartmentalization observed.

This study uses multinuclear MRI to assess early efficacy of stem cell therapy in stroke by monitoring sodium homeostasis and lactate levels in treated animals.

The paper analyzes sequence and structural variability in the SARS-CoV-2 nucleocapsid protein, finding high mutability and structural plasticity linked to enhanced viral assembly efficiency.

This paper designs and synthesizes SPIO-HGNS nanoparticles with tunable SPR in the NIR range to enhance photothermal conversion for potential photothermal therapies.

This study reveals how SARS-CoV-2 caps its RNA genome through an unconventional mechanism involving RNAylation and methyltransferase activity, identifying potential antiviral targets.

The paper shows that compressive forces stabilize microtubules in living cells through CLASP2 relocation, indicating mechano-responsive properties.

The paper shows that DPA4 and SOD7 repress CUC genes to prevent ectopic boundary fate and enable proper axillary meristem establishment and stem cell niche formation.

This study shows that nimesulide, an NSAID used in cattle, causes renal failure and death in Gyps vultures at concentrations found in treated cattle muscle.

This study optimizes urinary extracellular vesicle isolation methods and detects radiation-induced metabolomic changes using mass spectrometry.

This study identifies FOXM1 as a transcription factor that specifies and loads chromatin DNA fragments into extracellular vesicles via an LC3-dependent autophagosome-MVB pathway.

This study identifies complement component 1q (C1q) as a macrophage-derived factor that regulates gastrointestinal motility by interacting with the enteric nervous system.

This study identifies genomic regions and candidate genes associated with drought effects on chickpea phenology, revealing temperature-independent and temperature-dependent mechanisms and their adaptive implications.

This study tests if monetary rewards improve visual working memory performance but finds no effect on memory quality or intrinsic motivation.

This study shows that the LPS-TLR4 pathway promotes NETs formation in AACLF, exacerbating liver injury through mechanisms involving gut-derived LPS and neutrophil activity.

This study builds a 22-gene prognosis model for hepatocellular carcinoma using pyroptosis-related signatures, showing low-risk patients have significantly better survival.

This study identifies mTOR as a key determinant of chemosensitivity, showing that its inhibition promotes drug-tolerant senescence in cancer cells.

The paper analyzes the expansion and adaptive evolution of mTERF genes in plants, finding that M-class mTERF genes expanded via tandem duplication and evolved rapidly with positive selection in nucleic acid-binding sites.