Y. Xiao

The paper registers the BigBrain atlas with MNI PD25 and ICBM152 atlases to bridge histological and MRI data for neurological research and surgery.

This study identifies a role for MTF1 and copper in promoting myogenesis by enhancing MTF1 expression and its interaction with myogenic genes.

This paper shows how different ERK2 inhibitors shift conformational states by exploiting activation loop dynamics, affecting dephosphorylation rates.

This study shows PID1 increases lipolysis by inhibiting insulin's antilipolytic effect through the AKT/PKA/HSL pathway in adipose tissue.

The paper develops a microchip-based sequential secretion assay to analyze protein dynamics in single human macrophages, revealing distinct activation modes and states dependent on basal conditions.

The paper reports the structure of Ago2 bound to a target RNA using both seed and supplementary regions, showing supplementary interactions significantly enhance target affinity.

This study uses a microvasculature-on-a-chip system to analyze ex vivo dynamics of human glioblastoma cells, showing correlations with tumor heterogeneity and subtypes.

This study shows that VPAC1 and TRPV4 channel interaction promotes calcium-dependent gastric cancer progression through a positive feedback loop involving VIP secretion.

This paper introduces a BSA-Seq method for rapid gene cloning in maize by using whole genome sequencing of pooled F2 individuals to identify mutant genes.

This study reveals how phosphorylation and ubiquitin binding synergistically activate parkin by reorganizing its structure to facilitate ubiquitin transfer.

This study shows that HIV-1 antisense protein (ASP) from different clades induces autophagy through interaction with p62 and is regulated by autophagy and ubiquitin/proteasome systems.

This paper introduces a method to infer microbial ecological networks from steady-state data without assuming population dynamics models, validated on simulated and experimental datasets.

This study uses single-molecule techniques to characterize the type I-E CRISPR-Cas primed acquisition complex, revealing how Cascade, Cas3, and Cas1-Cas2 coordinate to recognize and acquire foreign DNA.

This study uses a population dynamics model to show that horizontal gene transfer affects microbial community stability and species coexistence by altering gene flux and direction.