Yulong Zhang

Intrinsic regulation of intestinal stem cell fate and homeostasis by Tet

This study identifies Tet as a critical regulator of intestinal stem cell establishment and homeostasis through single-nucleus transcriptomic analysis.

The novel variant IBDV induces inflammatory responses via VP3-mediated pyroptosis by directly targeting Caspase-9

This paper identifies that the novel variant IBDV induces inflammatory responses through VP3-mediated pyroptosis by directly targeting Caspase-9, with Serine 33 as a critical amino acid for this interaction.

Functional Characterization of PCWDEs VdCut1 and VdPL16 Reveals Their Critical Roles in Verticillium dahliae Pathogenicity

This study identifies VdCut1 and VdPL16 as critical PCWDEs in Verticillium dahliae pathogenicity by showing their roles in hyphal growth, conidiation, and plant cell wall degradation.

ER stress-induced TREM2 downregulation exacerbates platelet activation and myocardial infarction in patients with coronary artery disease

This study identifies TREM2 as a signaling hub linking ER stress, immune-inflammation, and platelet hyperactivity in CAD, showing that TREM2 downregulation exacerbates myocardial infarction and that TREM2-activating antibodies may offer therapeutic potential.