Author

Renata Oliveira Pereira

University of IowaORCID 0000-0001-5809-4669Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Assay:imaging· 2 Research Focus:metabolism & bioenergetics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Amber CrabtreeiD· 3 shared Andrea Gail MarshalliD· 3 shared Annet KiraboiD· 3 shared Antentor Othrell Hinton Jr.iD· 3 shared Edgar Garza LopeziD· 3 shared Jenny C. SchaferiD· 3 shared Mohd Mabood KhaniD· 3 shared Oleg KovtuniD· 3 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCell Biology

Amber CrabtreeORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Stress-Encoded Mitochondrial Plasticity: ATF4 Control of Mega-Mitochondria and Nanotunnel Communication

Amber Crabtree, Suraj Thapliyal, Mohd Mabood Khan, Edgar Garza Lopez, Andrea Gail Marshall, Calixto Pablo Hernandez Perez, Oleg Kovtun, Jenny C. Schafer, Dea Pulatani, Yuho Kim, Sepiso Kenias Masenga, Annet Kirabo, Jeremiah Afolabi, Melanie R. McReynolds, Renata Oliveira Pereira, , Antentor Othrell Hinton Jr.

This study identifies ATF4 as a master regulator of mitochondrial structural plasticity through a novel signaling axis, showing its role in stress-induced mitochondrial remodeling.

bioRxiv · May 5, 2026 · PreprintCell Biology

The MICOS Complex Regulates Mitochondrial Structure and Oxidative Stress During Age-Dependent Structural Deficits in the Kidney

Prasanna Katti, Praveena Prasad, Sepiso Kenias Masenga, Prasanna Venkhatesh, Zer Vue, Andrea Gail Marshall, Benjamin Rodriguez, Han Le, Edgar Garza Lopez, Alexandria C. Murphy, Brenita C. Jenkins, Ashlesha A. Kadam, Jianqiang Shao, Amber Crabtree, Pamela Martin, , Antentor Othrell Hinton Jr.

This study investigates age-related mitochondrial structural deficits in the kidney, finding that the MICOS complex is impaired, leading to increased oxidative stress and mitochondrial dysfunction.

Aging Cell · May 1, 2026Peer-reviewedPhysiology

ATF4 Coordinates Transcriptomic and Structural Adaptations in Aging Muscle

Amber Crabtree, Mohd Mabood Khan, Estêvão Scudese, Calixto Pablo Hernandez Perez, Prasanna Venkhatesh, Andrea Gail Marshall, Benjamin Rodriguez, Edgar Garza Lopez, Okwute Michael Ochayi, Estélio Henrique Martin Dantas, Pamela Martin, Matheus Baffi, Fabiana Rodrigues Scartoni, Margaret Mungai, Kit Neikirk, , Antentor Othrell Hinton Jr.

This study shows ATF4 coordinates transcriptomic and structural changes in aging muscle, linking it to mitochondrial dysfunction and suggesting the ISR pathway as a therapeutic target.

bioRxiv · Mar 30, 2026 · PreprintCell Biology

Altered Relaxation and Mitochondria-Endoplasmic Reticulum Contact Sites Precede Major (Mal)adaptations in Aging Skeletal Muscle and are Prevented by Exercise

Ryan J. Allen, Ana Kronemberger, Qian Shi, R. Marshall Pope, Elizabeth Cuadra‐Muñoz, Wangkuk Son, Long‐Sheng Song, Ethan J. Anderson, Renata Oliveira Pereira, Vitor Agnew Lira

This study identifies early aging-related changes in muscle MERC ultrastructure and proteome, which are reversed by exercise, suggesting potential therapeutic targets for sarcopenia.

Aging Cell · Jun 30, 2025Peer-reviewedPhysiology