Enrique Martínez-Pérez

This study uses C. elegans and mouse models to functionally validate infertility-associated genetic variants in MSH4, showing their pathogenic effects on meiotic processes in both sexes.

This study identifies a second mobile region in mHORMADs that controls their conformation and function, showing its conservation across species.

This study shows that in C. elegans male spermatogenesis, crossover-promoting factors can recruit to chromosomes without SPO-11 activity, indicating weakened crossover control compared to hermaphrodite oogenesis.

This paper uses automated behavioural tracking in C. elegans to phenotype 25 disease models, revealing both strong and subtle mutant effects that could aid drug repurposing.

The paper develops a self-sustained fungal bioluminescence system in animal models to monitor molecular events non-invasively.

This study identifies the HAL-2/HAL-3 complex as essential for regulating Polo-like kinase activity during C. elegans meiosis, ensuring proper homolog pairing and synaptonemal complex assembly.

The paper investigates piRNA biogenesis in nematodes, showing that piRNA upstream motifs are derived from snRNA promoter elements and that piRNA production depends on RNA polymerase II pausing and chromatin structure.