Marta Di Forti

Genomic Variation Predicts Real-Time Δ⁹-tetrahydrocannabinol Response in Humans

This study links genomic variation to real-time Δ9-THC response in humans, showing associations between CYP3A4 expression and psychotomimetic effects.

Co-expression-based models improve eQTL predictions and highlightnovel transcriptome-wide genes associated with schizophrenia

The paper introduces co-expression-based models to improve eQTL predictions and identifies novel schizophrenia-associated genes using brain RNA-seq data.

Investigating the Polygenic Relationship Between Cannabis Use and Schizophrenia in the All of Us Research Program

This study investigates the polygenic relationship between cannabis use and schizophrenia using data from the All of Us Research Program, finding independent associations between polygenic scores for cannabis use disorder and schizophrenia.

Multi-ancestry genetic architecture of sleep duration and its relationship to other sleep and psychiatric phenotypes

This paper conducts a multi-ancestry GWAS of sleep duration, identifying 234 genome-wide significant loci and showing distinct genetic architecture from other sleep and psychiatric traits.

Cross-ancestry genetic investigation of schizophrenia, cannabis use disorder, and tobacco smoking

This study investigates genetic correlations and causal relationships between schizophrenia, cannabis use disorder, and tobacco smoking across African and European ancestries, identifying pleiotropic loci and convergent genetic effects.

Association of extent of cannabis use and psychotic like intoxication experiences in a multi-national sample of First Episode Psychosis patients and controls

This study examines whether cannabis use extent predicts psychotic-like and euphoric intoxication experiences in First Episode Psychosis patients and controls, finding a significant interaction between caseness and use frequency.

Jumping To Conclusions, General Intelligence, And Psychosis Liability: Findings From The Multi-Centre EU-GEI Case-Control Study

The paper investigates the relationship between jumping to conclusions bias, IQ, psychosis, and polygenic risk scores in a case-control study, finding that IQ significantly predicts JTC bias while schizophrenia PRS does not.

Age-dependent genetic variants associated with longitudinal changes in brain structure across the lifespan

This study identifies genetic variants linked to longitudinal brain structure changes across the lifespan using MRI data from 15,640 individuals.

The independent and combined influence of schizophrenia polygenic risk score and heavy cannabis use on risk for psychotic disorder: A case-control analysis from the EUGEI study.

The paper examines the independent and combined effects of schizophrenia polygenic risk score and heavy cannabis use on psychotic disorder risk using EUGEI data, finding both factors independently increase risk.

Investigating the role of behaviour in the genetic risk for schizophrenia

This study examines the association between schizophrenia polygenic risk scores and 420 behavioural traits in the UK Biobank, identifying potential causal pathways and highlighting the need for further research.

Cannabis-associated symptom profiles in patients with first episode psychosis and population controls

This study examines the relationship between cannabis use and symptom profiles in first episode psychosis patients and population controls, finding that cannabis use correlates with positive symptoms and negative symptoms in patients.