Author

Carlos Relaño‐Rupérez

Spanish National Centre for Cardiovascular ResearchORCID 0000-0002-1407-9245Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:deconvolution· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Fátima Sánchez‐CaboiD· 3 shared Enrique Lara‐PezziiD· 2 shared Jorge Alegre‐CebolladaiD· 2 shared Laura LalagunaiD· 2 shared Laura Sen-MartíniD· 2 shared Abel Galicia Martín· 1 shared Alba Pau-NavalóniD· 1 shared Alejandro Clemente-MantecaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersDevelopmental Biology

Fátima Sánchez‐CaboORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Abnormal ventricular wall patterning precedes and drives MYBPC3 hypertrophic cardiomyopathy

Alejandro Salguero-Jiménez, Alba Pau-Navalón, Marcos Siguero-Álvarez, Carlos Relaño‐Rupérez, Javier Santos-cantador, Maria Sabater Molina, Xiaoxi Luo, Laura Lalaguna, Laura Sen-Martín, Daniel Martín Pérez, Abel Galicia Martín, Bin Zhou, Juan Antonio Bernal Rodríguez, Fátima Sánchez‐Cabo, Enrique Lara‐Pezzi, , José Luís de la Pompa

This study identifies abnormal ventricular wall patterning as a driver of MYBPC3-related hypertrophic cardiomyopathy through disrupted cardiomyocyte proliferation and Prdm16 regulation.

bioRxiv · Mar 30, 2026 · PreprintDevelopmental Biology

Titin cleavage is a driver of cardiomyocyte disengagement and reactive myocardial fibrosis

Miguel Ángel López-Unzu, María Rosaria Pricolo, Roberto Silva‐Rojas, Alejandro Clemente-Manteca, David Sánchez-Ortiz, Natalia Vicente, Diana Velázquez-Carreras, Cristina Morales, Manuel Gavilán-Herrera, Laura Sen-Martín, Ángel Fernández‐Trasancos, Verónica Labrador-Cantarero, Lucía Sánchez-García, Carlos Relaño‐Rupérez, Fátima Sánchez‐Cabo, , Jorge Alegre‐Cebollada

This study shows that titin cleavage drives cardiomyocyte disengagement and fibrosis in heart disease, contributing to myocardial remodeling.

bioRxiv · Apr 22, 2025 · PreprintPhysiology

SpatialDDLS: An R package to deconvolute spatial transcriptomics data using neural networks

Diego Mañanes, Inés Rivero-García, Carlos Relaño‐Rupérez, Miguel Torres, David Sancho, Daniel Jiménez‐Carretero, Carlos Torroja, Fátima Sánchez‐Cabo

SpatialDDLS deconvolutes spatial transcriptomics data using neural networks, showing accuracy and speed compared to existing methods.

Bioinformatics · Feb 1, 2024Peer-reviewedBioinformatics