Author

Liang Zhao

Complete Omics (United States)ORCID 0000-0002-2126-6778Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Liang Zhao4 papers · University of North Carolina at Chapel Hill

Biology Disciplines

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Molecular Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

David A. KassiD· 2 shared Kavita SharmaiD· 2 shared Mariam MeddebiD· 2 shared Mohammad KeykhaeiiD· 2 shared Navid KoleiniiD· 2 shared Benjamin G. Dubner· 1 shared Bogdan C. Paun· 1 shared Brian LiniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

David A. KassORCID

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Author profile →

3 papers

Recent·Most cited

Reduced Myocardial Serine Synthesis Impairs Functional, Metabolic, and Redox Adaptations to Cardiac Stress

Malihe Rezaee, Mohammad Keykhaei, Navid Koleini, Tegbir Panesar, Simiao Li, Nalini Salvekar, David J. Polhemus, Chengchen Hu, Mariam Meddeb, Liang Zhao, Kavita Sharma, Christopher J. Petucci, Nathaniel W. Snyder, Junichi Sadoshima, David A. Kass

This study shows that reduced myocardial serine synthesis impairs cardiac stress responses by disrupting redox balance, one-carbon metabolism, and amino acid homeostasis.

bioRxiv · Jun 2, 2026 · PreprintMolecular Biology

Serine auxotrophy is a targetable vulnerability driven by PSAT1 suppression in AML

Ilias Sinanidis, Panagiotis Tsakiroglou, Benjamin G. Dubner, Rebecca Foertsch, Julia Gondek, InYoung Choi, Bogdan C. Paun, Liang Zhao, Gabriel Ghiaur, William Brian Dalton

The paper identifies serine auxotrophy in AML as a vulnerability driven by PSAT1 suppression, showing sensitivity to serine/glycine restriction and potential therapeutic targeting.

bioRxiv · May 13, 2025 · PreprintCancer Biology

ATP Citrate Lyase Supports Cardiac Function and NAD+/NADH Balance And Is Depressed in Human Heart Failure

Mariam Meddeb, Navid Koleini, Seungho Jun, Mohammad Keykhaei, Farnaz Farshidfar, Liang Zhao, Seoyoung Kwon, Brian Lin, Gizem Keceli, Nazareno Paolocci, Virginia Shalkey Hahn, Kavita Sharma, Erika L. Pearce, David A. Kass

This study investigates the role of ATP citrate lyase (ACLY) in cardiac function and NAD+/NADH balance, finding it is reduced in heart failure and its inhibition impairs cardiac function and metabolism.

bioRxiv · Jun 9, 2024 · PreprintMolecular Biology