Author

Benjamin G. Dubner

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Gabriel GhiauriD· 2 shared William Brian DaltoniD· 2 shared Alexei M. BygraveiD· 1 shared Ben LangmeadiD· 1 shared Bogdan C. Paun· 1 shared Clayton P. SantiagoiD· 1 shared Dwight E. BerglesiD· 1 shared Eric Helmenstine· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Gabriel GhiaurORCID

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2 papers

Recent·Most cited

Serine auxotrophy is a targetable vulnerability driven by PSAT1 suppression in AML

Ilias Sinanidis, Panagiotis Tsakiroglou, Benjamin G. Dubner, Rebecca Foertsch, Julia Gondek, InYoung Choi, Bogdan C. Paun, Liang Zhao, Gabriel Ghiaur, William Brian Dalton

The paper identifies serine auxotrophy in AML as a vulnerability driven by PSAT1 suppression, showing sensitivity to serine/glycine restriction and potential therapeutic targeting.

bioRxiv · May 13, 2025 · PreprintCancer Biology

Cell-specific regulation of gene expression using splicing-dependent frameshifting.

Jonathan P. Ling, Alexei M. Bygrave, Clayton P. Santiago, Rogger P. Carmen‐Orozco, Vickie Trinh, Minzhong Yu, Yini Li, Ying Liu, Kyra D. Bowden, Leighton H. Duncan, Jeong Soon Han, Kamil Taneja, Rochinelle Dongmo, Travis A. Babola, Patrick Parker, , Seth Blackshaw

This paper introduces SLED, a splicing-based method to control gene expression in specific cell types, demonstrating its utility in targeting neurons, photoreceptors, and cancer cells.

Nature Communications · Oct 1, 2022Peer-reviewedMolecular Biology