Expansion Revealing of Pathology Resolves Nanostructures Associated with Inflammatory Phenotypes in COVID-19 Decedent Human Brain Tissue
Alice E. Stanton, Jinyoung Kang, Joel Blanchard, Carles A. Boix, Margaret E. Schroeder, Y S Lee, Hanquan Su, Shiwei Wang, Eunah Yu, Amauche Emenari, Zhuyu Peng, Emre Agbas, Oyku Cerit, Demian Park, Ruihan Zhang, , Li‐Huei Tsai
The paper introduces ExRPath and 15ExMPath techniques to expand human brain tissue for nanostructure analysis, revealing amyloid nanoclusters associated with SARS-CoV-2 in COVID-19 patients.
bioRxiv · May 15, 2026 · PreprintNeuroscience