The paper identifies sibling-derived chimerism in microglia and macrophages across marmoset tissues using single-cell RNA-seq, showing hematopoietic origin and regional variation in brain microglia.

eLife · Aug 14, 2026Peer-reviewedNeuroscience

Long-read transcriptomics highlights venom gland specialization and Inhibitor Cystine Knot (ICK) rich toxin diversity in Philippine tarantulas

Lorenz Rhuel P. Ragasa, Maria Mikaela U. Dumbrique, Sid Alfred S. Gamboa, Anj Guillan M. Baile, Darrell C. Acuña, Heidie Frisco Cabanos, Ricardo C.H. del Rosario, Leonardo A. Guevarra, Myla R. Santiago-Bautista

The paper presents the first long-read transcriptomic analysis of venom glands in Philippine tarantulas, revealing ICK toxin diversity and transcriptional signatures of venom specialization.

bioRxiv · Jul 18, 2026 · PreprintBioinformatics

Census and genetic analysis of the United States marmoset population

Murillo F. Rodrigues, Philberta Leung, Jamie A. Ivy, Alexandra M. Stendahl, Karina Ray, Jenna Castro, Samuel M. Peterson, Ricardo C.H. del Rosario, Simon Ploesch, Joanna Malukiewicz, Katinka A. Vigh‐Conrad, Benjamin N. Bimber, Marmoset Genetics Working Group, Jeffrey D. Wall, Donald F. Conrad

The paper analyzes the genetic diversity and population structure of US marmosets, revealing pre-colony population structure and generating a pedigree-based recombination map.

bioRxiv · May 21, 2026 · PreprintGenetics

Next-generation enhancer AAVs for selective interspecies targeting of midbrain dopaminergic neurons

Kian A. Caplan, Ke Chen, Martin Wienisch, Yongqi Wang, Ruoyang Chai, In-Hye Kang, Cindy Szyin Chen, Ricardo C.H. del Rosario, Fenna M. Krienen, Fan Wang, Guoping Feng

The paper develops and benchmarks enhancer-AAVs for selective targeting of midbrain dopaminergic neurons across species, identifying a specific enhancer and optimizing AAV backbones to improve specificity and efficiency.

bioRxiv · Nov 6, 2025 · PreprintNeuroscience

Genomic Insights into Derived Dwarfism and Exudivory in a Genus (Callithrix) of the World's Smallest Anthropoid Monkeys

Joanna Malukiewicz, Vanner Boere, Nelson H. A. Curi, Jorge Abdala Dergam, Claudia Igayara de Souza, Sílvia Bahadian Moreira, Patrícia Avello Nicola, Marcelo Passamani, Luiz CM Pereira, Ricardo C.H. del Rosario, Alcides Pissinatti, Daniel L. Silva, Ita de Oliveira e Silva, Carlos Ramon Ruiz-Miranda, Reed A. Cartwright, , Anne C. Stone

This study uses low-coverage whole genome sequencing to investigate the genomic basis of derived dwarfism and exudivory in Callithrix marmosets, identifying candidate genes under positive selection.

bioRxiv · May 19, 2025 · PreprintEvolutionary Biology

Structurally divergent and recurrently mutated regions of primate genomes

Yafei Mao, William T. Harvey, David Porubskỳ, Katherine M. Munson, Kendra Hoekzema, Alexandra P. Lewis, Peter A. Audano, Allison N. Rozanski, Xiangyu Yang, Shilong Zhang, DongAhn Yoo, David Gordon, Tyler Fair, Xiaoxi Wei, Glennis A. Logsdon, , Evan E. Eichler

The paper identifies structurally divergent regions in primate genomes and quantifies the impact of structural variants across multiple species.

Cell · Feb 29, 2024Peer-reviewedGenomics

A marmoset brain cell census reveals influence of developmental origin and functional class on neuronal identity

Fenna M. Krienen, Kirsten M. Levandowski, Heather Zaniewski, Ricardo C.H. del Rosario, Margaret E. Schroeder, Melissa Goldman, Martin Wienisch, Alyssa Lutservitz, Victoria F. Beja-Glasser, Cindy Chen, Qiangge Zhang, Ken Y. Chan, Katelyn X. Li, Jitendra Sharma, Dana M. McCormack, , Guoping Feng

The paper analyzes single-nucleus RNA sequencing data from marmoset brain cells to show that neuronal identity is more influenced by developmental origin than functional class.

Science Advances · Oct 12, 2023Peer-reviewedNeuroscience

Comparison of Mitogenomic and Mitochondrial Markers for the Phylogenetic and Evolutionary Study of Marmosets, with special focus on captive Callithrix jacchus

João Luiz Guedes da Fonseca, Ricardo C.H. del Rosario, Maria Adélia Borstelmann de Oliveira, Guoping Feng, Claudia S. Igayara, Steven A. McCarroll, Patrícia Avello Nicola, Luiz Cézar Machado Pereira, Jeffrey Rogers, Christian Roos, Joanna Malukiewicz

This study compares mitogenome and mtDNA control region markers to determine the ancestry and diversity of captive Callithrix jacchus marmosets, finding mitogenomes provide better resolved phylogenies.

bioRxiv · Sep 19, 2022 · PreprintGenetics

Innovations in Primate Interneuron Repertoire

Fenna M. Krienen, Melissa Goldman, Qiangge Zhang, Ricardo C.H. del Rosario, Marta Florio, Robert P. Machold, Arpiar B. Saunders, Kirsten M. Levandowski, Heather Zaniewski, Benjamin Schuman, Carolyn W.‐H. Wu, Alyssa Lutservitz, Christopher D. Mullally, Nora M. Reed, Elizabeth Bien, , Steven A. McCarroll

The paper profiles interneurons in primates and rodents to identify evolutionary innovations in brain cell types and their molecular features.

Nature · Sep 30, 2020Peer-reviewedNeuroscience