Daniel W. Bak

Promiscuous Metal Site in Hepatitis B Virus X Protein Binds anFe-S Cluster

This study identifies Fe-S cluster ligands in HBx, showing it binds both Fe-S and Zn, with implications for HBV replication and drug targeting.

A nitrite-responsive regulatory RNA locus sustains commensal resilience against nitrosative stress

This study identifies a nitrite-responsive regulatory RNA locus in Bacteroides thetaiotaomicron that enhances resilience to nitrosative stress during intestinal inflammation.

Discovery of a cluster in the PRRSV Nsp1α leader protease reveals host-virus interplay in its downstream functions

The paper identifies a [4Fe-4S] cluster in PRRSV Nsp1α leader protease, showing its role in modulating protease activity and host-virus interactions.

Rational engineering of facultative anaerobiosis enables commensal survival in the oxygenated gut

This study engineers obligate anaerobic bacteria to tolerate oxygen, improving their survival in the gut.

Exploring metalloproteome remodeling in calprotectin-stressed Acinetobacter baumannii using chemoproteomics

This study uses chemoproteomics to show that calprotectin stress in Acinetobacter baumannii leads to undermetalation of metalloproteomes, impairing key metabolic and cellular processes.