Author

Judith Agudo

Dana-Farber Cancer InstituteORCID 0000-0002-3576-3169Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Assay:imaging· 2 Research Focus:spatial domain detection· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Jeremy L. MuhlichiD· 2 shared Peter Karl SorgeriD· 2 shared Aaron C. LiuiD· 1 shared Abigail A. JaquishiD· 1 shared Adam NelsoniD· 1 shared Adrienne Gropper WaksiD· 1 shared Alexander P. GottliebiD· 1 shared Alexander V. ChervonskyiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

Jeremy L. MuhlichORCID

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Author profile →

4 papers

Recent·Most cited

Dietary cysteine enhances intestinal stemness via CD8+ T cell-derived IL-22

Fangtao Chi, Qiming Zhang, Jessica E.S. Shay, Shixun Han, Johanna ten Hoeve, Yin Yuan, Zhenning Yang, Heaji Shin, Samuel Block, Sumeet A. Solanki, Yatrik Madhukar Shah, Matthew G. Vander Heiden, Judith Agudo, Ömer H. Yilmaz

This study shows that dietary cysteine improves intestinal stem cell repair through IL-22 from CD8+ T cells.

Nature · Oct 1, 2025Peer-reviewedCell Biology

Expansion of mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis

Abigail A. Jaquish, Eleni Phung, Xutong Gong, Pilar Baldominos, Silvia Galván-Peña, Ian Magill, Isabelle Bursulaya, Eleonora Marina, Aaron C. Liu, Alexander V. Chervonsky, Alexandra Cassano, Alia Welsh, Ananda W. Goldrath, Andrea Lebron Figueroa, Ankit Malik, , Deepshika Ramanan

The paper examines T cell changes in mammary glands during pregnancy and lactation, finding an expansion of T effector cells and similarities to intestinal T cells.

Nature Immunology · Jul 29, 2025Peer-reviewedImmunology

Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma

Tanjina Kader, Jia‐Ren Lin, Clemens B. Hug, Shannon Coy, Yu‐An Chen, Ino de Bruijn, Natalie N. C. Shih, Euihye Jung, Roxanne J. Pelletier, Mariana Lopez Leon, Gabriel Mingo, Dalia K. Omran, Jong Suk Lee, Clarence Yapp, Baby Anusha Satravada, , Sandro Santagata

This study uses spatial profiling to show immune suppression and microenvironment changes in fallopian tube precursors of high-grade serous ovarian cancer.

Cancer Discovery · Dec 20, 2024Peer-reviewedCancer Biology

An estrogen receptor signaling transcriptional program linked to immune evasion in human hormone receptor-positive breast cancer

Kenichi Shimada, Daniel E. Michaud, Yvonne Xiaoyong Cui, Kelly Zheng, Jonathan L. Goldberg, Zhenlin Ju, Stuart J. Schnitt, Ricardo Pastorello, Lukas D. Kania, John Hoffer, Jeremy L. Muhlich, Nhan Hyun, Robert Krueger, Alexander P. Gottlieb, Adam Nelson, , Jennifer L. Guerriero

This study identifies an estrogen receptor signaling program in HR+ breast cancer that suppresses immune responses by reducing T cell infiltration and HLA expression, suggesting therapeutic targets to enhance immunogenicity.

bioRxiv · Nov 23, 2024 · PreprintCancer Biology