Mark A. Watson

This study identifies that plasma proteins selectively reflect tissue-specific aging processes in muscle and ovary, revealing context-dependent age-related changes.

This study identifies age-related molecular changes in postmenopausal ovaries using proteomics, revealing dynamic remodeling and new biological insights.

The paper uses single-nucleus profiling to show age-related changes in the postmenopausal ovary, which are counteracted by parity.

The paper identifies a distinct p16INK4a-associated senescence signature in human ovarian tissue through proteogenomic profiling and spatial analysis.

The paper establishes a senotype of doxorubicin-induced senescence in postmenopausal human ovarian tissue using single nuclei sequencing and proteomics.

This study identifies ADAM19 as a modulator of the senescence-associated secretory phenotype (SASP) and shows that its inhibition reduces gut permeability and senescence markers in multiple species.

This study identifies Musashi as a regulator of intestinal stem cell function in Drosophila, showing its role in improving survival and gut permeability after radiation exposure.