Marta Florio

Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice

This study shows that HCN-channel dysfunction in neural progenitors causes microcephaly by disrupting cell cycle progression and proliferation in mice.

Role for the Na+/K+ ATPase α 3 subunit in folding and lamination of the human neocortex

This study identifies ATP1A3 variants in children with polymicrogyria and maps ATP1A3 expression patterns in human neocortex development using single-cell RNA sequencing.

Innovations in Primate Interneuron Repertoire

The paper profiles interneurons in primates and rodents to identify evolutionary innovations in brain cell types and their molecular features.

Extracellular matrix-inducing Sox9 orchestrates basal progenitor proliferation and gliogenesis in developing neocortex

This study shows Sox9 regulates basal progenitor proliferation and gliogenesis in the developing neocortex through ECM induction and integrin signaling.

Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex

The paper identifies human-specific genes preferentially expressed in fetal neocortex progenitors and shows they have distinct cell-type specificity compared to ancestral paralogs.