Terry D. Hinds

Mitochondrial carrier SLC25A34 links clock, diet, and temperature control of interorganellar lipid cycling

This paper identifies SLC25A34 as a key regulator of interorganellar lipid cycling, integrating circadian rhythms, diet, and temperature to control thermogenic metabolism.

Estrogen Receptor Beta Localized on Ventral Tegmental Area Dopamine Neurons Regulates Nicotine Self-Administration Acquisition in Ovary-Intact Female Rats

This study shows that estrogen receptor beta on VTA dopamine neurons reduces nicotine self-administration in female rats by decreasing dopamine neuron firing.

A comparison of adiponectin-deficient mice reveals the fundamental role of intracellular adiponectin

This study compares adiponectin-deficient mice to show that intracellular globular adiponectin regulates adipose tissue metabolism by modulating PPARγ activity.

Conditional deletion of CEACAM1 causes hepatic stellate cell activation

This study shows that CEACAM1 loss in hepatic stellate cells (HSCs) activates them, leading to myofibroblastic transformation and fibrosis without insulin resistance or steatosis.

GalNAc-siRNA Mediated Knockdown of Ketohexokinase Versus Systemic, Small Molecule Inhibition of its Kinase Activity Exert Divergent Effects on Hepatic Metabolism in Mice on a HFD

This study compares the effects of GalNAc-siRNA-mediated KHK knockdown and small molecule KHK inhibition on hepatic metabolism in mice on a high-fat diet, finding divergent impacts on lipid metabolism and glucose tolerance.