Author

Véronique Bourdeau

Centre Hospitalier de l’Université de MontréalORCID 0000-0002-9044-2106Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metabolomics· 1

Frequent Co-Authors

Gerardo FerbeyreiD· 4 shared Andreea R. SchmitzeriD· 2 shared Sebastian IgelmanniD· 2 shared Ana Maria Duman· 1 shared Daina Zofija AvizonisiD· 1 shared David J. PapadopoliiD· 1 shared Emilie LavalléeiD· 1 shared Farzaneh Mohebali· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersCancer Biology

Gerardo FerbeyreORCID

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Author profile →

4 papers

Recent·Most cited

Lactate-fueled hydride transfer metabolon drives breast cancer metastasis

Sebastian Igelmann, Predrag Jovanovic, Véronique Bourdeau, Nicolas Curdy, Lesley Zhan, Ranveer Palia, David J. Papadopoli, Daina Zofija Avizonis, Marilène Paquet, Shannon McLaughlan, Tara Nincic-Gajic, Lorne Taylor, Jean‐François Trempe, Josie Ursini‐Siegel, Gerardo Ferbeyre, Ivan Topisirović

This study identifies a lactate-fueled metabolon involving LDHB and HTC that promotes breast cancer metastasis by reprogramming NAD metabolism.

bioRxiv · Jun 21, 2026 · PreprintCancer Biology

Biguanide-PROTACs: Modulating Mitochondrial Proteins in Pancreatic Cancer Cells

Julie Vatté, Véronique Bourdeau, Gerardo Ferbeyre, Andreea R. Schmitzer

This study synthesizes Biguanide-PROTACs and evaluates their activity on pancreatic cancer cells, finding structure-permeability-activity relationships and some AMPK activation.

Molecules · Nov 12, 2024Peer-reviewedCancer Biology

The Role of ATP Synthase Subunit e (ATP5I) in Mediating the Metabolic and Antiproliferative Effects of Metformin

Guillaume Lefrançois, Emilie Lavallée, Marie‐Camille Rowell, Véronique Bourdeau, Farzaneh Mohebali, Thierry Bertomeu, Ana Maria Duman, Maya Nikolova, Mike Tyers, Simon‐Pierre Gravel, Andreea R. Schmitzer, Gerardo Ferbeyre

This paper identifies ATP5I as a target of metformin, showing its role in mediating metabolic and antiproliferative effects through mitochondrial dysfunction and altered ATP synthase oligomerization.

bioRxiv · Sep 20, 2024 · PreprintCancer Biology

The retinoblastoma tumor suppressor limits ribosomal readthrough during oncogene induced senescence

Neylen Del Toro, Frédéric Lessard, Jacob Bouchard, Nasrin Mobasheri, Jordan Guillon, Sebastian Igelmann, Sarah Tardif, Tony Buffard, Véronique Bourdeau, Léa Brakier‐Gingras, Gerardo Ferbeyre

The paper shows that the retinoblastoma protein (RB) prevents ribosomal readthrough during oncogene-induced senescence, acting as a caretaker tumor suppressor.

Biology Open · Oct 22, 2021Peer-reviewedMolecular Biology