Author

Aude G. Chapuis

University of WashingtonORCID 0000-0002-9574-5448Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Charanjit SinghiD· 1 shared Chuyi WangiD· 1 shared Clara McCurdyiD· 1 shared Donny Gun· 1 shared Emily Y. Chen· 1 shared Gerardo Javier· 1 shared Ioanna Panagi· 1 shared Jakob BakhtiariiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

Charanjit SinghORCID

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2 papers

Recent·Most cited

Collagen-binding IL-12 expressing STEAP1 CAR-T cells reduce toxicity and eradicate mouse prostate cancer in combination with checkpoint inhibitors

Koichi Sasaki, Vipul Bhatia, Yuta Asano, Jakob Bakhtiari, Pooja Kaur, Chuyi Wang, Takumi Matsuo, Olivier Dubois, Po-Chuan Chiu, Donny Gun, Charanjit Singh, Ioanna Panagi, Laurine Noblecourt, Maria Nikolaidi, Truman Chong, , Jun Ishihara

Nature Biomedical Engineering · Oct 23, 2025Peer-reviewedBioengineering

Overcoming immune evasion from post-translational modification of a mutant KRAS epitope to achieve TCR-T cell-mediated antitumor activity

Jihoon William Lee, Emily Y. Chen, Taylor Hu, Rachel Perret, Mary E. Chaffee, Tijana Martinov, Shwetha Mureli, Clara McCurdy, Lisa Anne Jones, Philip R. Gafken, Pritha Chanana, Yapeng Su, Aude G. Chapuis, Philip H Bradley, Thomas M. Schmitt, Philip D. Greenberg

Tumor cell methylation of KRASG12V epitope in HLA-A2 permits immune evasion, and new TCRs were generated to overcome this with engineered cell therapy.

bioRxiv · Sep 18, 2024 · PreprintImmunology