Author

Nicholas K. O’Neill

Boston UniversityORCID 0000-0002-9953-9940Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Benjamin L. WoloziniD· 2 shared Adam Thomas LabadorfiD· 1 shared Andrew F. TeichiD· 1 shared Ann Carolyn McKeeiD· 1 shared Benjamin J. SnyderiD· 1 shared Brittany N. DuggeriD· 1 shared Carol A. Miller· 1 shared Christine S. ChengiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersGenetic & Genomic Medicine

Benjamin L. WolozinORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Transcriptome-wide association study of Alzheimer disease reveals many differentially expressed genes and multiple biological pathways in brain tissue from African American donors

Mark W. Logue, Adam Thomas Labadorf, Nicholas K. O’Neill, Dennis W. Dickson, Brittany N. Dugger, Margaret E. Flanagan, Matthew P. Frosch, Marla Gearing, Lee‐Way Jin, Julia Kofler, Richard P Mayeux, Ann Carolyn McKee, Carol A. Miller, Melissa Erin Murray, Peter T. Nelson, , Lindsay A. Farrer

This study identifies differentially expressed genes and pathways in Alzheimer's disease brain tissue from African American donors, highlighting potential targets for treatment.

medRxiv · Oct 29, 2024 · PreprintGenetic & Genomic Medicine

Single cell transcriptomic profiling of tauopathy in a novel 3D neuron-astrocyte coculture model

Hannah Rickner, Lulu Jiang, Rui Hong, Nicholas K. O’Neill, Chromewell A. Mojica, Benjamin J. Snyder, Lushuang Zhang, Dipan Shaw, Maria Medalla, Benjamin L. Wolozin, Christine S. Cheng

The paper develops a 3D neuron-astrocyte coculture model to study tauopathy, showing it recapitulates pathological features and responds to HSP90 inhibitor treatment.

bioRxiv · May 3, 2022 · PreprintNeuroscience