Author

Kristopher J. Schmit

University of LuxembourgORCID 0000-0003-4983-9934Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 1

Frequent Co-Authors

Manuel ButtiniiD· 4 shared Pierre GarciaiD· 4 shared Alessia SciortinoiD· 3 shared Michel Guy André MittelbronniD· 3 shared Djalil CoowariD· 2 shared Enrico GlaabiD· 2 shared Mélanie H. ThomasiD· 2 shared Nathalie NicotiD· 2 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersNeuroscience

Manuel ButtiniORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Transcriptional Dysregulation in the Hippocampus of a murine model for Parkinson's Disease Cognition Impairment is Driven by Sex, Age, and Alpha-synuclein overexpression

Alessia Sciortino, Thomas Hentrich, Sergio Helgueta, Pierre Garcia, Kristopher J. Schmit, Mélanie H. Thomas, Rashi Halder, Djalil Coowar, Michel Guy André Mittelbronn, Lasse Sinkkonen, Julia Maria Schulze-Hentrich, Manuel Buttini

bioRxiv · Jul 18, 2025 · PreprintNeuroscience

Dietary fibre deprivation and bacterial curli exposure shift gut microbiome and exacerbate Parkinson's disease-like pathologies in an alpha-synuclein-overexpressing mouse

Kristopher J. Schmit, Alessia Sciortino, Velma T. E. Aho, Pierre Garcia, Beatriz Pardo Rodriguez, Mélanie H. Thomas, Jean‐Jacques Gérardy, Rashi Halder, Camille Cialini, Tony Heurtaux, Irati Bastero Acha, Irina Ostahi, Eric C. Martens, Michel Guy André Mittelbronn, Manuel Buttini, Paul Wilmes

This study shows that dietary fibre deprivation and bacterial curli exposure worsen PD-like symptoms in mice overexpressing human alpha-synuclein.

bioRxiv · Mar 21, 2022 · PreprintNeuroscience

A new synuclein-transgenic mouse model for early Parkinson's reveals molecular features of preclinical disease

Diana M. Hendrickx, Pierre Garcia, Amer Ashrafi, Alessia Sciortino, Kristopher J. Schmit, Heike Kollmus, Nathalie Nicot, Tony Kaoma, Laurent Vallar, Manuel Buttini, Enrico Glaab

This study uses a synuclein-transgenic mouse model to identify molecular changes in early Parkinson's disease before neurodegeneration occurs.

Molecular Neurobiology · Sep 30, 2020Peer-reviewedNeuroscience

Neurodegeneration and neuroinflammation are linked, but independent of alpha-synuclein inclusions, in a seeding/spreading mouse model of Parkinson disease

Pierre Garcia, Wiebke M. Wemheuer, Oihane Uriarte Huarte, Kristopher J. Schmit, Annette Masuch, Simone Brioschi, Andreas Weihofen, Eric Koncina, Djalil Coowar, Tony Heurtaux, Enrico Glaab, Rudi Balling, Carole Sousa, Alessandro Michelucci, Tony Kaoma, , Manuel Buttini

The paper investigates the role of alpha-synuclein spreading and inclusions in Parkinson disease using a mouse model, finding that neurodegeneration and microgliosis occur independently of inclusions.

bioRxiv · Aug 5, 2020 · PreprintNeuroscience