Author

Karin A. Ziegler

German Centre for Cardiovascular ResearchORCID 0009-0002-9364-3349Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Stefan Hanns EngelhardtiD· 2 shared Alina Griebel· 1 shared Ana Isabel DomingosiD· 1 shared Anandhakumar Chandran· 1 shared Andrea RaimondiiD· 1 shared Anselm I. UgwujaiD· 1 shared Antoneta GavociiD· 1 shared Anxhela ZhitiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Stefan Hanns EngelhardtORCID

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2 papers

Recent·Most cited

The perineurium integrates leptin with its sympathetic outflow to protect against obesity

Gitalee Sarker, Emma Rose Haberman, Anandhakumar Chandran, Thomas Monfeuga, Cyrielle Maroteau, Sofia Hult Lundh, Davi Sidarta-Oliveira, Andrea Raimondi, Karin A. Ziegler, Tiago Gomes, Tiago N. Cordeiro, Karishma Parekh, Emilia Schmid, Paola Fernández-Sanmartín, Alina Griebel, , Ana Isabel Domingos

This study identifies perineurial cells as integrators of leptin and sympathetic outflow, showing their role in obesity protection through barrier function and beta 2 adrenergic receptor regulation.

Nature Metabolism · Jul 13, 2026Peer-reviewedNeuroscience

Polyglutamylation of microtubules drives neuronal remodeling

Antoneta Gavoci, Anxhela Zhiti, Michaela Rusková, Maria M. Magiera, Mengzhe Wang, Karin A. Ziegler, Torben Johann Hausrat, Anselm I. Ugwuja, Shreyangi Chakraborty, Stefan Hanns Engelhardt, Matthias Kneussel, Martin Balaštík, Carsten Janke, Thomas Misgeld, Monika S. Brill

The paper shows that polyglutamylation of microtubules regulates neuronal remodeling by marking them for severing, affecting synapse and axon pruning in both peripheral and central circuits.

Nature Communications · Jun 25, 2025Peer-reviewedCell Biology