Sung Yeon Kim

PIEZO1 mediates mechanosensing and myofibroblastic activation of synovial fibroblasts in post-traumatic osteoarthritis

This study identifies PIEZO1 as a critical mediator of myofibroblast activation and fibrosis in post-traumatic osteoarthritis through mechanosensing mechanisms.

Decorin-mediated Extracellular Matrix Stabilization Maintains Cartilage Integrity During Aging

This study identifies decorin-mediated extracellular matrix stabilization as a key factor in maintaining cartilage integrity during aging, showing its role in preventing age-associated osteoarthritis.

CD14 plays a critical role in pain and inflammation across multiple models of post-traumatic osteoarthritis

The study shows CD14 is critical for pain and inflammation in post-traumatic osteoarthritis and that blocking CD14 can reduce pain and mobility loss.

Mechano-activation of synovial fibroblasts and macrophages during OA progression in the dynamically stiffening synovial microenvironment

This study investigates how synovial microenvironment stiffness changes during OA progression and how it affects fibroblast and macrophage behavior through mechanosignaling and cell-cell interactions.