host-pathogen & immune response

Host availability, climate and pupal-stage ecology shape the predicted environmental suitability of the New World screwworm across Central and South America

A global post-transcriptional regulator directs Acinetobacter baumannii carbon preference and gut colonization

This study identifies CsrA as a global regulator of carbon preference and gut colonization in Acinetobacter baumannii, revealing its role in repressing arginine/ornithine catabolism and enhancing competitive fitness.

Metagenomic Insights into the Fecal Microbiome, Resistome, and Mobilome of Beef Cattle in Cow-Calf Operations in Florida, United States

The paper analyzes the fecal microbiome, resistome, and mobilome of beef cattle in Florida, finding differences in ARG abundance between cows and calves and a notable proportion of ARGs on plasmids.

Changes in anterior cingulate connectivity associated with response to antidepressant treatment for major depressive disorder

This study examines changes in anterior cingulate cortex connectivity in response to antidepressant treatment in MDD patients, finding distinct patterns associated with treatment response and remission.

Disease dynamics during ecosystem restoration and faunal reassembly

This study uses a model to show that disease dynamics during ecosystem restoration depend on pathogen transmissibility, timing of slow life history species establishment, and community assembly, not just biodiversity.

Integrating bacterial genomics and host transcriptomics links Burkholderia pseudomallei variation to melioidosis mortality and neutrophil responses

Psychoneuroimmunology of Viral Hepatitis and Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis

This study conducts a systematic review and meta-analysis of 24 studies to explore the link between viral hepatitis, hepatocellular carcinoma, and neuropsychiatric disorders, identifying immune and inflammatory mechanisms.

A tabular foundation model rivals established species distribution models from presence-only records

This paper evaluates tabular foundation models as species distribution models, finding they perform competitively without per-dataset tuning but are sensitive to biased data.

Proliferation and mutation as humoral immune response

This study models the affinity maturation process to assess the roles of proliferation and mutation in the humoral immune response, finding that multiple strategies can yield optimal outcomes.

Endothelial protein C receptor is an entry receptor for Langya virus

This study identifies the endothelial protein C receptor (EPCR) as the entry receptor for Langya virus and reveals the molecular basis of its interaction with the viral attachment glycoprotein.

Concussion decreases brain signal variability

This study shows that concussion reduces BOLD signal variability in specific brain networks, linking it to symptom severity and cognitive decline.

Body size cascades from Neodiprion sawfly hosts to Perilampid parasitoids: An investigation of sequential divergence

The paper investigates whether parasitoid body size and morphology diverge in response to host species differences in Neodiprion sawflies, supporting sequential divergence.

Invasion analysis for structured populations: analytical principles and numerical workflows

The paper develops a framework for analyzing invasion in structured populations using analytical and numerical methods to determine invasion success across different ecological scenarios.

Compositional computations in the primate frontal cortex

The paper investigates how neural circuits in the primate frontal cortex support compositional generalization by separating computations into spatial and temporal components and identifying biases when these components are misaligned.

Dopamine synthesis capacity and tau pathology differentially modulate rest-to-task functional network dynamics

This study examines how dopamine synthesis and tau pathology affect functional brain network dynamics during rest and task performance in young and older adults.

Infant Sensory Over-Responsivity: Relations to Early Life Adversity, Emerging Behavioral Problems, and Sensory Functional Connectivity

This study identifies prenatal adversity and neonatal brain connectivity as predictors of infant sensory over-responsivity, which links to later behavioral problems.

Intra-individual changes to peak alpha frequency map to pain perception following high frequency sensitisation of central nociceptive pathways: A test-retest reliability study

This study examines intra-individual changes in peak alpha frequency and -band power in EEG data following high-frequency sensitisation of central nociceptive pathways, assessing test-retest reliability and their relation to pain perception.

The behaviour bends, the code holds: working-memory category information in the multiple-demand network across graded interruption

This study investigates how the multiple-demand network maintains working memory during task interruptions, finding that neural representations of category information remain stable despite behavioral costs.

Ecology of gene drives: Organism fitness under larval competition determines gene drive performance

This study investigates how larval competition affects gene drive performance in Aedes aegypti mosquitoes using agent-based models and Bayesian optimization.

Distinct patterns of multisensory integration underly the expression of flavor preferences and aversions in rats

This study shows that rats integrate taste and smell signals differently depending on the valence of flavor components, challenging the MLE framework for multisensory integration.

Basal ganglia output guides decision-making by state destabilization

The paper shows that basal ganglia output in zebrafish destabilizes neural activity states to guide decision-making in a Go/No-go task.

Serum Calprotectin as predictor of Rheumatoid Arthritis disease severity and Mortality

This study evaluates serum calprotectin as a biomarker for disease activity, severity, cardiovascular risk, and mortality in inflammatory rheumatic diseases, finding it to be a better predictor than CRP in certain contexts.

Knockdown of fibrillarin reveals cell- and virus- dependent restriction of henipavirus replication and enhanced antiviral immune signalling

This study shows that fibrillarin depletion affects henipavirus replication differently across cell types and viruses, and enhances antiviral immune signaling.

Self-Other Neural Representational Distinction is Associated with Distorted Social Predictions in Social Anxiety

This study investigates how social anxiety affects self-other neural distinctions and social predictions, finding that higher SA correlates with greater self-other representational separation in the pgACC and altered prediction tracking in the precuneus.

Strategy-dependent causal relationships between large-scale cortical activity and perceptual decisions

The paper investigates how different decision-making strategies in mice affect cortical activity and identifies frontal cortex involvement in engaged strategies.

Cortical bursts provide spatio-temporal frames for the large-scale phase synchrony emerging across the birth transition

The paper examines how cortical bursts influence phase synchrony development in preterm infants and links persistent phase-based connectivity to poorer neurocognitive outcomes.

ADRA2B genetic polymorphism modulates vagus nerve stimulation response

This study investigates how a genetic polymorphism in ADRA2B affects responses to vagus nerve stimulation, finding it influences pupillary responses and cortical activity alignment with noradrenergic projections.

Imipramine binds to amyloid-β and extends the survival of Alzheimer's disease patients

This study shows imipramine binds to amyloid-β, reduces Aβ accumulation, and improves survival in Alzheimer's patients.

Chronic hypertension disrupts the blood-brain barrier in the ventral hippocampus in females but not males in a rat model of vascular cognitive impairment

This study shows chronic hypertension increases BBB permeability and anxiety-like behaviors in female rats but not males in a vascular cognitive impairment model.

Using refuge plants to manage resistance evolution and crop yield in agricultural fields

This study shows that varying toxicity and refuge frequency over pest generations is more effective for managing pesticide resistance than keeping them constant, with outcomes depending on population parameters and mating behaviors.