Air Quality and Health Impacts

Air pollution from biomass burning disrupts early adolescent cortical microarchitecture development

This study examines how exposure to PM2.5 from biomass burning affects cortical microstructure development in adolescents using neuroimaging data.

Clonal hematopoiesis associated non-small cell lung cancer risk is potentiated by small particulate matter air pollution

This study finds that clonal hematopoiesis of indeterminate potential (CHIP) doubles non-small cell lung cancer (NSCLC) risk in non-smokers, and this risk is further increased by exposure to high levels of PM2.5 air pollution.

Particulate matter composition drives differential molecular and morphological responses in lung epithelial cells

The paper shows that different particulate matter mixtures cause distinct molecular and morphological changes in lung epithelial cells, with heavy metals causing more severe effects.

Impact of carbon monoxide on neural activation during a reaction time task

This study examines the effects of low-level carbon monoxide exposure on reaction times and BOLD fMRI activation during a simple reaction time task in healthy participants.

Maternal diesel exposure and maternal choline supplementation interactions in fetal and placental immune factors

This study examines how maternal diesel exposure and choline supplementation interact to affect fetal and placental immune factors, revealing region- and sex-specific effects on inflammation and microglial morphology.

Integrated Genomics Approaches Identify Mediators of Transcriptional and Epigenetic Responses to Afghan Desert Particulate Matter in Human Small Airway Epithelial Cells

The paper uses ATAC-seq and PRO-seq to study transcriptional and epigenetic responses to Afghan desert particulate matter in human small airway epithelial cells, identifying key pathways and transcription factors involved.

Subacute Inhalation of Ultrafine Particulate Matter Triggers Inflammation Without Altering Amyloid Beta Load in 5xFAD mice.

Long-term effects of wildfire smoke exposure during early-life on the nasal epigenome in rhesus macaques

This study identifies long-term epigenetic changes in rhesus macaques exposed to wildfire smoke during early life, showing methylation differences and gene expression changes linked to immune and nervous system processes.

A novel gene-by-environment quantitative trait locus on mouse chromosome 15 underlies susceptibility to acute ozone-induced lung injury

This study identifies a novel gene-by-environment QTL on mouse chromosome 15 associated with susceptibility to acute ozone-induced lung injury using the Collaborative Cross panel.

Severity of early life stress moderates the effect of fine particle air pollution on adolescent brain development

The paper shows that early life stress severity moderates the effect of PM2.5 air pollution on adolescent brain volume changes.