Eating Disorders and Behaviors

Temporal dynamics of cognitive flexibility in adolescents with anorexia nervosa: a high density EEG study

This study uses high-density EEG to examine temporal brain dynamics of cognitive flexibility in adolescents with anorexia nervosa and their relationship with anxiety.

Prefrontal cortical protease TACE/ADAM17 is involved in neuroinflammation and stress-related eating alterations

This study shows that TACE/ADAM17 in the prefrontal cortex is involved in stress-induced eating changes and neuroinflammation in rats.

Central extended amygdala neurons in the development of activity-based anorexia

This study identifies PKC-δ neurons in the central extended amygdala as critical regulators of activity-based anorexia, showing their necessity for the development of key anorexia-like behaviors.

The impact of anorexia nervosa and BMI polygenic risk on childhood growth: a 20-year longitudinal population-based study

This study examines the association between polygenic scores for anorexia nervosa and BMI with growth trajectories over 20 years in children, finding sex-specific effects and potential risk interactions.

An EEG study on the effect of being overweight on anticipatory and consummatory reward in response to pleasant taste stimuli

This study examines how overweight individuals respond to food cues and consumption using EEG, finding reduced attention to cues but no difference in reward response.

The Phenome-wide Consequences of Anorexia Nervosa Genes

This study uses transcriptomic imputation to translate AN GWAS findings into gene expression associations, revealing 47 genes linked to AN and their clinical consequences in a biobank cohort.

Aberrant Functional Connectivity between Reward and Inhibitory Control Networks in Pre-Adolescent Binge Eating Disorder

This study identifies reduced functional connectivity between reward and inhibitory control networks in pre-adolescent children with binge eating disorder compared to controls.

Eating disorder symptoms and their associations with anthropometric and psychiatric polygenic scores

The paper investigates genetic associations between eating disorder symptoms and polygenic scores for psychiatric, metabolic, and anthropometric traits in adolescents.

Neural Representations of Food-Related Attributes in the Human Orbitofrontal Cortex During Choice Deliberation in Anorexia Nervosa

The paper decodes neural representations of taste and health attributes in the OFC during food choices in AN patients and healthy individuals, finding stronger health-related associations in AN.

Relationship between impulsivity, uncontrolled eating and body mass index: a hierarchical model

The paper examines the relationship between impulsivity, uncontrolled eating, and BMI using structural equation models and MRI data, finding associations between impulsivity traits and BMI via uncontrolled eating.

Systems genetic analysis of binge-like eating in a C57BL/6J x DBA/2J-F2 cross

The paper identifies genetic loci influencing binge-like eating in mice using a cross between C57BL/6J and DBA/2J strains, finding sex-specific and combined QTLs.

Prefrontal responses during proactive and reactive inhibition are differentially impacted by stress in anorexia and bulimia nervosa

The paper examines how stress affects proactive and reactive inhibition in bulimia nervosa and anorexia nervosa binge-purging subtype using fMRI and behavioral tasks.

Emotional responsiveness task in emotional distress: correlated of functional neuroimaging in anorexia and bulimia

The paper investigates neural correlates of emotional processing in anorexia and bulimia patients using a distress paradigm, finding no group differences in emotional response but higher clinical scores and alexithymia.

Can't decide how much to EAT? Effort variability for reward is associated with cognitive restraint

The paper examines the relationship between variability in reward seeking and eating behaviors, finding that greater effort variability is linked to lower cognitive restraint.

Differential expression of deltaFosB in reward processing regions between binge eating prone and resistant female rats

The paper compares deltaFosB expression in reward processing regions between binge eating prone and resistant female rats, finding higher expression in BEP rats in certain brain areas.

Brain activation and connectivity in anorexia nervosa and body dysmorphic disorder when viewing bodies: relationships to clinical symptoms and perception of appearance

This study compares brain activation and connectivity in anorexia nervosa and body dysmorphic disorder when viewing bodies, finding distinct and overlapping neural patterns related to clinical symptoms and appearance perception.

Short-term fasting selectively influences impulsivity in healthy individuals

This study examines how short-term fasting affects four types of impulsivity in healthy individuals, finding impaired action inhibition and reduced reflection impulsivity during fasting.

Molecular neuroanatomy of anorexia nervosa

This study identifies brain regions and genes associated with anorexia nervosa using transcriptomic data and genetic variants.

Suppression of cortico-striatal circuit activity improves cognitive flexibility and prevents body weight loss in activity-based anorexia in rats

Investigating resting brain perfusion abnormalities and target-engagement by intranasal oxytocin in women with bulimia nervosa and binge-eating disorder and healthy controls

This study examines resting brain perfusion differences in women with bulimia nervosa/binge-eating disorder and healthy controls, and evaluates if intranasal oxytocin normalizes perfusion in affected brain circuits.

Polygenic score for body mass index is associated with disordered eating in a general population cohort

The paper investigates the association between BMI polygenic scores and disordered eating behaviors in a general population cohort, finding a positive link mediated by BMI.

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

The paper estimates genetic correlations between eating disorder and substance-use-related phenotypes using GWAS data, finding both positive and negative associations.

Neural mechanisms of perceptive and affective processing of body stimuli in Anorexia nervosa - are there developmental effects?

This study investigates neural mechanisms of body image processing in adolescents and adults with Anorexia nervosa using fMRI, finding differential activation patterns in specific brain regions.

The demyelinating agent cuprizone induces a male-specific reduction in binge eating in the binge-prone C57BL/6NJ strain

This study shows that cuprizone reduces binge eating specifically in male C57BL/6NJ mice, suggesting sex-specific mechanisms influenced by genetic background.

Structural neuroimaging signatures of anorexia nervosa features in a mixed sample enriched for disease vulnerability

The paper identifies structural neuroimaging signatures of anorexia nervosa symptoms and risk factors in a sample enriched for disease vulnerability using MRI and DTI data.

White matter microstructure in women with acute and remitted anorexia nervosa: an exploratory neuroimaging study

This study examines white matter microstructure changes in women with acute and remitted anorexia nervosa using diffusion MRI, finding increased diffusivity indices in affected groups compared to healthy controls.

Cyfip1 haploinsufficiency increases compulsive-like behavior and modulates palatable food intake: Implications for Prader-Willi Syndrome

This study shows that Cyfip1 haploinsufficiency increases compulsive-like behavior and modulates palatable food intake in a parent-of-origin and genetic background-dependent manner in mice.

Association between uncontrolled eating and caudate responses to reward cues

The paper examines the link between uncontrolled eating and caudate responses to reward cues in normal-weight individuals, finding a positive correlation independent of impulsivity.

Altered brain function in anorexia nervosa and bulimia nervosa: A hierarchical series of task-based fMRI meta-analyses

This paper conducts a meta-analysis of fMRI studies on anorexia nervosa and bulimia nervosa, finding limited convergence in brain activity across different tasks and patient groups.

The reality of "food porn": Larger brain responses to food-related cues than to erotic images predict cue-induced eating.

The paper shows that greater brain response to food cues than erotic images predicts more eating in response to food cues.