Reproductive Physiology in Livestock

Membrane progesterone receptors PAQR6 and PAQR8 in the ruminant uterus and ovary

This study maps the expression of PAQR6 and PAQR8 in ruminant reproductive tissues using antibodies and qPCR, showing their localization and dynamic gene expression changes during pregnancy.

Conceptus attachment coincides with initiation of an anti-inflammatory cytokine profile in the pig endometrium

The paper investigates the transition from pro- to anti-inflammatory states in the pig endometrium during blastocyst attachment, identifying key genes and cell types involved in inflammation resolution.

Uterocalin: a protein uniquely specialised to support mobile encapsulated embryos of horses, rhinos and tapirs

This study identifies uterocalin as a specialized protein supporting embryo nutrition and capsule formation in equids, rhinos, and tapirs, showing unique amino acid and structural features across perissodactyls.

Evaluation of IGF1 and MKI67 relative abundance of mRNA transcript in relation to histopathological features of equine endometrosis

The paper evaluates mRNA transcript abundance of IGF1, MKI67, TGFB1, and ACTA2 in equine endometrosis samples and links them to histopathological features.

Effects of hCG or GnRH Treatment on Embryonic Mortality and Reproductive Performance in Buchi sheep of Cholistan Desert, Pakistan

This study evaluates the effects of hCG and GnRH treatments on reproductive performance and embryonic mortality in Buchi sheep, finding hCG more effective in improving progesterone levels and litter size.

Vaginal and uterine microbiomes in beef cattle at artificial insemination and associations with pregnancy outcomes

The paper analyzes vaginal and uterine microbiomes in beef cattle at artificial insemination to identify associations with pregnancy outcomes using shotgun metagenomic sequencing.

Establishment and functional characterization of bovine endometrial epithelial organoids

This study establishes bovine endometrial epithelial organoids and shows they produce fluid supporting embryo development beyond Day 8 under conventional culture conditions.

Nuclear factor kappa B subunits and IkappaB family are modulated in the ovine endometrium during early pregnancy

This study examines changes in NF-κB subunits and IκB family expression in ovine endometrium during early pregnancy, finding altered mRNA and protein levels that may support maternal immune tolerance.

Bovine endometrial organoids: A new tool to study conceptus-maternal interactions in mammals

The paper develops a bovine endometrial organoid model to study hormone responsiveness and conceptus-maternal interactions, identifying differentially expressed genes and biological processes.

Dynamic cytokine interplay governing implantation and immune tolerance in pregnant pigs

The paper examines cytokine changes during pig pregnancy, finding that pregnant pigs show increased cytokine levels indicating immune modulation, while non-pregnant pigs have stable levels.

Study on Early pregnancy diagnosis in sows based on joint analysis of vaginal secretion metabolomics and machine learning

This study identifies biomarkers for early pregnancy diagnosis in sows using metabolomic analysis and machine learning, finding three key metabolites with high diagnostic accuracy.

Endometrial microbiome in mares with and without clinical endometritis

This study compares the uterine microbiomes of mares with and without clinical endometritis, finding significant differences in composition that may influence disease development.

Short- and long-term effects of uterine disease on oocyte developmental capacity in postpartum dairy cows

This study investigates the impact of uterine disease on oocyte developmental capacity in dairy cows, finding reduced cleavage rates in oocytes collected at 1 month and 80 days postpartum but not at 165 days postpartum.

The Testing of Copper Intrauterine Devices to Mitigate Uterine Infections in Mares: A Preliminary Study

This study evaluates a copper intrauterine device (CuiUPOD) for reducing uterine infections in mares, showing improved outcomes with higher copper concentrations.

Adenomyosis and fibrosis define the morphological memory of the postpartum uterus of dairy cows previously exposed to metritis.

This study shows that early postpartum metritis in dairy cows leads to long-term uterine morphology changes, including adenomyosis and fibrosis, which affect reproductive success.

Comparative cell free salivary miRNA profile in Bubalus bubalis between diestrus and estrus stages

The paper identifies differentially expressed miRNAs in buffalo cell-free saliva during estrus and diestrus to explore their potential as estrus biomarkers.

A 3D endometrium-on-a-chip reveals the role of conceptus-derived factors CAPG and PDI in conceptus-endometrial communication

This paper develops a 3D bovine endometrium-on-a-chip system to study conceptus-derived factors CAPG and PDI's effects on endometrial transcriptome and secretome.

Effects of parity and early pregnancy on peripheral blood leukocytes in dairy cattle

This study examines how parity and early pregnancy affect immune cell populations and function in dairy cattle, finding differences in immune responses between heifers and cows that may explain reduced fertility.

Reproductive Tract Microbial Transitions from Late Gestation to Early Postpartum Using 16S rRNA Metagenetic Profiling in First-Pregnancy Heifers

This study examines microbial transitions in the reproductive tract of first-pregnancy heifers from late gestation to early postpartum using 16S rRNA sequencing, identifying distinct microbial profiles in the vagina and uterus.

Biosensor capability of the endometrium is mediated in part, by altered miRNA cargo from conceptus-derived extracellular vesicles.

The paper investigates how endometrial biosensor capability is influenced by miRNA cargo in conceptus-derived extracellular vesicles during peri-implantation, showing differential miRNA effects on endometrial gene expression.

Effects of conceptus proteins on endometrium and blood leukocytes of dairy cattle using transcriptome and meta-analysis

This study examines the effects of IFNT and PAG on endometrial and blood leukocyte transcriptomes in dairy cattle, identifying differentially expressed genes and their biological functions.

Long noncoding RNAs and mRNAs profiling in ovary during laying and broodiness in Taihe Black-Bone Silky Fowls (Gallus gallus domesticus Brisson)

This study identifies differentially expressed mRNAs and lncRNAs in the ovaries of broody and high egg-laying Taihe Black-Bone Silky Fowls, revealing potential genes and pathways involved in broodiness and egg production.

Metagenomic analysis unravels novel taxonomic differences in the uterine microbiome between healthy mares and mares with endometritis

This study identifies taxonomic differences in the uterine microbiome between healthy mares and mares with endometritis using 16S rRNA sequencing.

Central Role for Glycolysis and Fatty Acids in LH-responsive Progesterone Synthesis

This study identifies metabolic pathways, including glycolysis and fatty acid synthesis, essential for LH-stimulated progesterone production in ovarian luteal cells.

Sperm exposure to accessory gland secretions alters the transcriptomic response of the endometrium in cattle

The study shows that ejaculated sperm, exposed to accessory gland secretions, induce a different endometrial transcriptomic response than epididymal sperm in cattle.

Integrated Transcriptomic and Metabolomic Profiling of Sheep Ovarian Tissues Confer their association in Fecundity associated Pathways

This study integrates transcriptomic and metabolomic data from sheep ovarian tissues to identify gene-metabolite associations linked to fecundity pathways.

Comparative Analysis of Ovarian Transcriptome Changes Across Gestational Stages in Kari Sheep

This study uses RNA-Seq to analyze ovarian transcriptome changes in Kari sheep across gestational stages, identifying differentially expressed genes and their functional associations.

Extensive rewiring of the gene regulatory interactions between in vitro-produced conceptuses and endometrium during attachment

The paper identifies extensive gene regulatory rewiring between in vitro-produced conceptuses and endometrium during implantation, contributing to pregnancy loss in cattle.

An exploratory data analysis from ovine and bovine RNA-seq identifies pathways and key genes related to cervical dilatation

The paper analyzes RNA-seq data from cattle and sheep to identify genes and pathways associated with cervical dilatation during reproductive cycles.

Sex-bias in utero alters ovarian reserve but not uterine capacity in female offspring

This study investigates the effects of in-utero sex bias on reproductive traits in female pigs, finding that birth weight has a greater impact than litter sex ratio on ovarian reserve and uterine development.