Forensic and Genetic Research

Long runs of homozygosity are correlated with marriage preferences across global population samples

The paper shows that cousin marriage preferences increase long runs of homozygosity (ROH) in global populations by 1.5 times, but marriage practices explain only a small portion of ROH variation.

Genetic Landscape of Gullah African Americans

This study analyzes the genetic structure of Gullah African Americans, finding higher African ancestry and lower European admixture compared to non-Gullah African Americans.

The genetic structure of Norway

This study examines the genetic structure of the Norwegian population, identifying two distinct genetic regions and highlighting the impact of geography on migration patterns and ancestry.

Reconstructing the human genetic history of mainland Southeast Asia: insights from genome-wide data from Thailand and Laos

This study uses genome-wide SNP data from 33 ethnolinguistic groups in Thailand and Laos to reconstruct the genetic history of Mainland Southeast Asia, revealing language-based genetic structure and admixture events.

DamageProfiler: Fast damage pattern calculation for ancient DNA

DamageProfiler is a Java-based tool for analyzing damage patterns in ancient DNA, providing user-friendly interfaces and output formats for integration into analysis pipelines.

Early Alpine human occupation backdates westward human migration in Late Glacial Europe

The paper presents genomic data from a Late Epigravettian individual in Italy dated to 16,980-16,510 cal BP, showing genetic replacement associated with the emergence of Late Epigravettian culture, pushing back the spread of a Balkan/Anatolian genetic component by 3,000 years.

The Forensic Landscape and the Population Genetic Analyses of Hainan Li Based on Massively Parallel Sequencing DNA Profiling

This study characterizes the forensic genetic polymorphism of Hainan Li population using MPS-based DNA profiling and establishes population genetic datasets for further analysis.

Why most Principal Component Analyses (PCA) in population genetic studies are wrong

The paper shows PCA results in population genetics are unreliable and can be manipulated, suggesting a need for alternative methods.

Genetic-substructure and complex demographic history of South African Bantu speakers

This study investigates genetic substructure and demographic history of South African Bantu speakers using genome-wide data, revealing fine-scale population structure aligned with geography and linguistics.

Calculating the divergence time by direct comparison between individuals and the out-group

The paper recalculates divergence times between populations using SNPs from the 1000 Genomes Project by comparing individuals to an out-group.

An LR framework incorporating sensitivity analysis to model multiple direct and secondary transfer events on skin surface

The paper develops a Bayesian logistic regression framework with sensitivity analysis to model DNA transfer and persistence on skin surfaces, incorporating multiple contacts and background DNA.

Archaeogenomic Distinctiveness of the Isthmo-Colombian Area

The paper analyzes genomic data from Indigenous groups in Panama to reveal pre-Hispanic demographic changes and the genetic structure of the Isthmo-Colombian area.

Fine-scale population structure reveals high genetic heterogeneity of the Kuwaiti population in the Arabian Peninsula

This study identifies high genetic heterogeneity in the Kuwaiti population by analyzing genome-wide SNP data from 583 individuals, revealing distinct subgroups with different ancestral origins.

The First complete Zoroastrian-Parsi Mitochondria Reference Genome: Implications of mitochondrial signatures in an endogamous, non-smoking population

The paper generates the first complete mitochondrial reference genome for Zoroastrian-Parsis, identifies genetic variants, and links them to longevity and disease, while highlighting the impact of endogamy and non-smoking culture on mutational signatures.

Impact of modular mitochondrial epistatic interactions on the evolution of human subpopulations

The paper analyzes mitochondrial genome variation across human populations to identify co-mutation patterns and epistatic interactions, finding subpopulation-specific biases in mutation clustering.

Personalized genealogical history inferred from biobank-scale IBD segments

The paper infers genealogical history and social behaviors from IBD segments in UK Biobank data, revealing population-scale genetic connections and regional family preferences.

Calculating likelihoods and likelihood ratios at SNPs-based mixtures. A reappraisal of the binomial inference, as applied to forensic identity tests

The paper re-evaluates binomial inference for SNP-based forensic mixtures, introducing NITZq to calculate likelihood ratios and comparing it to EUROFORMIX.

Genomic analyses of 10,376 individuals provides comprehensive map of genetic variations, structure and reference haplotypes for Chinese population

The paper presents genomic analyses of 10,376 Chinese individuals, identifying novel genetic variations and providing a reference haplotype map, along with an imputation server for improved accuracy.

Massively parallel sequencing of 165 ancestry-informative SNPs and forensic biogeographical ancestry inference in three southern Chinese Sinitic/Tai-Kadai populations

The paper evaluates an ancestry panel using 165 SNPs in three southern Chinese populations, showing improved forensic performance over STR-based systems but limitations in intercontinental ancestry inference.

Genomic and demographic processes differentially influence genetic variation across the X chromosome

The paper examines how mutation, recombination, selection, and demography shape genetic variation across different regions of the human X chromosome using data from 26 populations.

Mitochondrial Genome Diversity in the Central Siberian Plateau with Particular Reference to Prehistory of Northernmost Eurasia

The paper analyzes mitochondrial genome diversity in the Central Siberian Plateau to trace genetic connections between the Yenisei-Sayan region and Northeast Eurasia over the last 10,000 years.

Maternal lineages from 10-11th century commoner cemeteries of the Carpathian Basin

The paper analyzes maternal lineages from 10-11th century commoner cemeteries in the Carpathian Basin, finding they differ from elites and show admixture with eastern immigrant groups.

Estimating divergence times from DNA sequences

This paper introduces two methods for estimating divergence times from DNA sequences using coalescent theory and demonstrates their robustness to demographic complexities.

A scalable pipeline for local ancestry inference using tens of thousands of reference haplotypes

This paper introduces Ancestry Composition, a pipeline for ancestry deconvolution that uses over 14,000 reference haplotypes to improve accuracy and scalability.

Sex identification of ancient pinnipeds using the dog genome

The paper tests the use of the dog genome for sex identification in ancient pinnipeds by analyzing X chromosome read ratios and applies it to archaeological samples.

Complex genetic admixture histories reconstructed with Approximate Bayesian Computations

This paper develops an ABC framework to reconstruct complex admixture histories using simulated genetic data and applies it to African American and Barbadian populations.

The genetic landscape of Ethiopia: diversity, intermixing and the association with culture

This study examines the genetic structure of Ethiopians, linking cultural and geographic factors to genetic diversity and intermixing across 68 ethnic groups.

Large-scale Inference of Population Structure in Presence of Missingness using PCA

EMU accurately infers population structure from ultra-low coverage sequencing data with missingness, outperforming existing methods on real and simulated datasets.

Integrating linguistics, social structure, and geography to model genetic diversity within India

The paper models genetic diversity in India by integrating geography, language, and social structure, finding language and social factors most influential in shaping genetic patterns.

Analysis of human mitochondrial genome co-occurrence networks of Asian population at varying altitudes

The paper analyzes mitochondrial genome co-occurrence networks in Asian populations at different altitudes to understand high altitude adaptation mechanisms.