Forensic and Genetic Research

Assessing the Performance of qpAdm: A Statistical Tool for Studying Population Admixture

This study evaluates qpAdm's performance in admixture analysis through simulations, finding it robust in many scenarios but cautioning against certain practices.

Genome Diversity in Ukraine

This study provides genome-wide data for the Ukrainian population, identifying novel genetic variants and highlighting its unique genetic diversity.

Recent fluctuations in Mexican American genomes have altered the genetic architecture of biomedical traits

The paper shows that increased Amerindigenous ancestry in Mexican Americans over time has altered the genetic architecture of traits like height and polygenic risk scores.

Haplotype and Population Structure Inference using Neural Networks in Whole-Genome Sequencing Data

HaploNet uses neural networks to infer population structure from whole-genome sequencing data, outperforming standard methods in distinguishing closely related populations.

A genetic history of the pre-contact Caribbean

This study uses genome-wide data from pre-contact Caribbean individuals to trace population movements and genetic continuity across the region.

Whole Genome Sequencing-based Characterization of Human Genome Variation and Mutation Burden in Botswana

The paper characterizes human genomic variations and mutation burden in Botswana using whole genome sequencing, identifying damaging variants and admixture patterns.

More rule than exception: Parallel evidence of ancient migrations in grammars and genomes of Finno-Ugric speakers

This study finds parallel genetic and linguistic patterns among Finno-Ugric speakers and their neighbors, suggesting population-level convergence and possible origins in the Pontic-Caspian steppes.

Prediction Of Eye, Hair And Skin Color In Admixed Populations Of Latin America

The paper evaluates prediction accuracy for eye, hair, and skin pigmentation in admixed Latin Americans using genomic and phenotypic data, finding that Random Forest and regression perform best, and that pigmentation SNPs improve accuracy, especially for skin color.

Identity-by-descent detection across 487,409 British samples reveals fine-scale population structure, evolutionary history, and trait associations

The paper detects identity-by-descent segments in 487,409 UK Biobank samples to reveal population structure, evolutionary history, and trait associations.

Kinship and social organization in Copper Age Europe. A cross-disciplinary analysis of archaeology, DNA, isotopes, and anthropology from two Bell Beaker cemeteries

The paper analyzes kinship and social organization in two Copper Age Bell Beaker cemeteries using archaeological, genetic, isotopic, and anthropological data.

Local Ancestry Prediction with PyLAE

PyLAE predicts local ancestry from whole-genome sequencing or high-density genotyping data, efficiently handling large numbers of ancestral populations.

Genomic Insights into the Demographic History of Southern Chinese

Genome-wide SNPs from 211 Southern Chinese, analysed with over 1,200 ancient and modern genomes, split the Yangtze River Farmer lineage into four language-linked sub-ancestries and date later migrations.

Early Medieval Genetic Data from Ural Region Evaluated in the Light of Archaeological Evidence of Ancient Hungarians

This study analyzes genetic data from the Ural region and Hungary to show genetic continuity and connections between ancient Uralic populations and the Carpathian Basin.

A dynamic 6,000-year genetic history of Eurasia's Eastern Steppe

This study reconstructs the 6,000-year genetic history of the Eastern Steppe using ancient genomes, revealing pastoralist expansions, population structuring, and the emergence of the Xiongnu and Mongols.

A systematic investigation of human DNA preservation in medieval skeletons

This study evaluates DNA preservation in ten skeletal elements from Medieval Germany, confirming the petrous pyramid as the best source and identifying seven alternative locations for aDNA extraction.

The genetic and linguistic structures of Abyssinians and their neighbor reveal the historical demographic dynamics and environmental adaptation in the African Horn region.

Graph Embedding Method Based Genetical Trajectory Reveals Migration History Among East Asians

This study uses a graph embedding method to reconstruct the migration history of East Asian populations using SNP data from the 1000 Genomes Project and identifies SNPs associated with neurological diseases.

Probabilistic estimation of identity by descent segment endpoints and detection of recent selection

The paper estimates IBD segment endpoints with uncertainty quantification and detects recent selection signals using UK Biobank data.

The genomic formation of First American ancestors in East and Northeast Asia

The paper shows Ancient Beringians have admixture from Amur River Basin populations and are not the deepest American lineage.

On the heterozygosity of an admixed population

The paper derives a relationship between heterozygosity and admixture proportions in admixed populations, showing that heterozygosity is at least as high as the least heterozygous source population.

South Asian patient population genetics reveal strong founder effects and high rates of homozygosity - new resources for precision medicine

The paper characterizes the genetic structure of South Asian populations, identifies founder effects and high homozygosity, and develops a custom SNP array for genetic studies in the region.

Ancient mitochondrial DNA pathogenic variants putatively associated with mitochondrial disease

This study identifies pathogenic mitochondrial DNA variants in ancient Eurasian populations, revealing their presence in tRNA genes and potential clinical significance.

Population genomics of the Viking world

This study analyzes ancient genomes from the Viking Age to understand genetic structure and migration patterns, finding significant foreign gene flow and population differentiation.

Dutch population structure across space, time and GWAS design

The paper analyzes Dutch population structure using genome-wide data, identifying haplotypic clusters and showing that fine-grained haplotypic covariates reduce GWAS confounding.

Relative matching using low coverage sequencing

This study shows that low coverage sequencing can effectively match relatives with genotyping arrays, achieving similar accuracy for close relatives and strong correlation for distant ones.

A paleogenetic perspective of the Sabana de Bogota (Northern South America) population history over the Holocene (9000 - 550 cal BP)

The paper analyzes mitochondrial genetic diversity in the Sabana de Bogota region to assess genetic continuity or discontinuity in prehispanic populations over the Holocene.

Bioarchaeological analysis of one of the earliest Islamic burials in the Levant

This study presents the first genomic analysis of early Islamic burials in the Levant, finding genomic similarity to modern Bedouins and Saudis rather than neighboring Levantine groups.

Inferring the ancestry of parents and grandparents from genetic data

This paper introduces a method to estimate ancestry proportions of an individual's parents and grandparents using genetic data, showing it can distinguish between different ancestry combinations in ancestors.

GENis, an open-source multi-tier forensic DNA information system

GENis is an open-source forensic DNA database system that supports local, regional, and national levels with security features and a Bayesian framework for cold hit analysis.

MicroHapDB: a portable and extensible database of all published microhaplotype marker and frequency data

MicroHapDB compiles published microhaplotype marker and frequency data to aid in forensic DNA marker development and population studies.