Forensic and Genetic Research

Exploration of deep-learning based classification with human SNP image graphs

This study explores using deep convolutional neural networks to classify human populations based on SNP image graphs from genome-wide data, achieving high accuracy in some cases.

Detecting Selection in Low-Coverage High-Throughput Sequencing Data using Principal Component Analysis

The paper introduces two selection statistics for detecting selection signals in low-coverage sequencing data using PCAngsd, showing they control false positives and match results from high-quality genotypes.

Ancestry Inference Using Reference Labeled Clusters of Haplotypes

ARCHes infers ancestry composition using haplotype-based models, outperforming RFMix in global and local ancestry assignment across diverse populations.

Ancient genomes reveal long range influence of the site and culture of Tiwanaku

The paper analyzes ancient genomes from Tiwanaku to show genetic homogeneity in the Lake Titicaca Basin over 1200 years but genetic diversity in ritual core individuals, suggesting foreign influence.

Indigenous ancestry and admixture in the Uruguayan population

The paper uses whole-genome sequencing to analyze indigenous ancestry in Uruguayans, identifying Amerindian genetic heritage and estimating admixture timing.

Inference of recent admixture using genotype data

This paper improves BGA inference methods to account for recent admixture, showing improved accuracy and a likelihood ratio test for detecting recent admixture in genotype data.

EXAMINING DISCRIMINATION PERFORMANCE AND LIKELIHOOD RATIO VALUES FOR TWO DIFFERENT LIKELIHOOD RATIO SYSTEMS USING THE PROVEDIT DATASET

This paper compares two likelihood ratio systems using the PROVEDIt dataset to evaluate their discrimination performance and LR value differences.

Open-Access STRS Database Of Populations From The 1000 Genomes Project Using High Coverage Phase 3 Data

The paper genotypes 22 STR markers from 1000 Genomes Project data using HipSTR, creating an open-access database showing reliable allele frequencies and population separation.

Peopling of Tibet Plateau and multiple waves of admixture of Tibetans inferred from both modern and ancient genome-wide data

This paper uses modern and ancient genome-wide data to infer multiple waves of admixture and the peopling of the Tibet Plateau, identifying genetic connections and population stratifications among Tibetans and East Asians.

Projecting ancient ancestry in modern-day Arabians and Iranians: a key role of the past exposed Arabo-Persian Gulf on human migrations

The paper models ancestry in Arabians and Iranians, finding strong west-east population structure and evidence linking east Arabians to basal Eurasians.

AFA: Computationally efficient Ancestral Frequency estimation in Admixed populations: the Hispanic Community Health Study/Study of Latinos

AFA estimates ancestral allele frequencies in admixed populations with high accuracy, showing strong correlation with gnomAD frequencies in the Hispanic Community Health Study/Study of Latinos.

The Genomic History of the Middle East

This study analyzes 137 Middle Eastern genomes to reveal population history, ancestry, and selection patterns, showing no out-of-Africa expansions but elevated Basal Eurasian ancestry in Arabians.

A curated dataset of modern and ancient high-coverage shotgun human genomes.

The paper curates a dataset of 34 high-coverage shotgun human genomes, including ancient and modern samples, along with the genetic pipeline used for processing.

Ancestral contributions to contemporary European complex traits

This study connects genetic ancestry from three ancient populations to complex traits in Estonian Biobank samples, finding ancestry-specific contributions to traits like BMI and blood cholesterol.

Combining Ancient DNA And Radiocarbon Dating Data To Increase Chronological Precision

This paper shows that combining ancient DNA and radiocarbon dating can narrow date ranges for related individuals by incorporating biological constraints on death age separations.

Using Y-chromosome capture enrichment to resolve haplogroup H2 shows new evidence for a two-Path Neolithic expansion to Western Europe

This study introduces a Y-chromosome capture assay (YMCA) to improve NRY coverage and haplogroup resolution, revealing new evidence for a two-path Neolithic expansion to Western Europe.

Genomic insights into the differentiated population admixture structure and demographic history of North East Asians

This study analyzes genome-wide SNP data from 510 individuals across 38 Mongolic, Tungusic, and Sinitic populations to explore genetic structure, admixture history, and demographic patterns in North-East Asia.

Climate and mountains shaped human ancestral genetic lineages

This paper models the impact of climate and terrain on human ancestral genetic lineages, showing that these factors explain lineage divergence and migration patterns.

Genome-scale sequencing and analysis of human, wolf and bison DNA from 25,000 year-old sediment

The paper retrieves and analyzes low-coverage mammalian ancient genomes from 25,000-year-old sediments, revealing new insights into the genetic history of humans, wolves, and bison.

The first insight into the genetic structure of the population of modern Serbia

This paper presents the first dataset of clinically relevant gene variants in the Serbian population, identifying unique genetic determinants and their potential health impacts.

Human inbreeding has decreased in time through the Holocene

This study shows inbreeding frequency decreased over time in ancient Eurasian populations, linked to population growth from agricultural practices.

Exceptional ancient DNA preservation and fibre remains of a Sasanian saltmine sheep mummy in Chehrabad, Iran

The paper reports the whole genome sequencing of a 1600-year-old mummified sheep from a salt mine, showing exceptional DNA preservation and linking it to modern Southwest Asian breeds.

Human mobility at Tell Atchana (Alalakh) during the 2nd millennium BC: integration of isotopic and genomic evidence

This study integrates isotopic and genomic data from Tell Atchana to examine human mobility during the 2nd millennium BC, finding limited individual mobility despite high regional interaction.

Continental-scale genomic analysis suggests shared post-admixture adaptation in Americas

The paper identifies shared post-admixture adaptation patterns in the Americas by analyzing genomic data from 6,000 admixed individuals, highlighting regions associated with immune response and disease traits.

Revisiting the STRmixlikelihood ratio probability interval coverage considering multiple factors

The paper evaluates the coverage of a probabilistic genotyping system by testing multiple layers of conservativism and finds improved precision with extended MCMC runs.

Testing methods for quantifying Monte Carlo variation for categorical variables in Probabilistic Genotyping

The paper tests two methods for quantifying Monte Carlo variation in probabilistic genotyping, finding both fall short of achieving 99% coverage but provide additional conservatism.

New insights from the combined discrimination of modern/ancient genome-wide shared alleles and haplotypes: Differentiated demographic history reconstruction of Tai-Kadai and Sinitic people in South China

The paper reconstructs the demographic history of Tai-Kadai and Sinitic people in South China using genome-wide data and reference datasets, revealing genetic contributions from millet and rice farmers.

Significant East Asian affinity of Chinese Hui genomic structure suggesting their predominant cultural diffusion model in the genetic formation process

This study analyzes genomic data to determine the origin and genetic structure of Chinese Hui people, finding strong East Asian affinity and supporting a cultural diffusion model over demic diffusion.

Inferring population histories for ancient genomes using genome-wide genealogies

This paper introduces methods to infer population histories using ancient genomes and genealogies, revealing insights into population dynamics and mutation rates in ancient populations.

Significant (Z|-4|) admixture signal with a source from ancient Wusun observed in contemporary Bulgarians.

The paper identifies significant Central Asian ancestry in Bulgarians and early medieval populations, linking it to the Wusun tribes and suggesting historical migration patterns.