Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Toward an Objective Assessment of Fight-or-Flight System Function in Anxiety Disorders: Startle Reflex Modulation in Threat Coping Contexts as a Candidate Neurophysiological Marker of Disrupted Defense System Operation

The paper assesses startle reflex modulation in threat coping contexts to evaluate defensive system function in anxiety disorders and finds correlations with anxiety, depression, and worry symptoms.

Internet-delivered cognitive behavioral therapy is associated with distinct blood small RNA profiles in panic disorder

This study identifies distinct blood small RNA profiles in panic disorder patients before and after internet-delivered cognitive behavioral therapy, linking specific microRNAs and tRFs to treatment response and immune pathways.

A longitudinal naturalistic fMRI study of trait anxiety and cross-phase consistency in subjective fear signature expression

This study examines how trait anxiety relates to cross-phase consistency in subjective fear neural signatures using longitudinal fMRI data.

Mapping the neural circuitry of cognitive restructuring in depressive and anxiety disorders

The paper investigates neural circuitry differences during cognitive restructuring in depressive and anxiety disorders using fMRI, finding distinct activation and connectivity patterns associated with symptom severity.

The heritability of reinforcement learning parameters and their association with anxiety

The paper examines the heritability of reinforcement learning parameters related to anxiety, finding extinction learning rates correlate with anxiety severity but show no heritability, while safety learning rates have modest heritability but no genetic overlap with anxiety.

Self-esteem modulates beneficial causal attributions in the formation of novel self-beliefs

This study examines how self-esteem and depression influence causal attributions and self-belief formation through a computational model of learning.

Neural dynamics underlying the persistence of perseverative thought in depression and anxiety

This study investigates how neural dynamics in depression and anxiety contribute to the persistence of perseverative thought using fMRI and network control theory.

Social Anxiety Increases Autonomic and Visuocortical Generalization of Conditioned Aversive Responses to Faces

This study shows that social anxiety disorder is linked to broader generalization of aversive responses to faces, with increased visuocortical and pupil dilation responses to facial stimuli.

Heightened subcortical reactivity to uncertain-threat is associated with future internalizing symptoms, conditional on stress exposure

The paper identifies heightened subcortical reactivity to uncertain-threat as a predictor of future internalizing symptoms in individuals with low stress exposure.

Absence of Systematic Effects of Internalizing Psychopathology on Learning Under Uncertainty

This study investigates the relationship between internalizing psychopathology and learning under uncertainty, finding no systematic effect on learning rates or task performance.

Implicit Emotional Biases in Anxiety and Depression: A Fast Periodic Visual Stimulation Study

This study uses FPVS to show that anxiety patients have stronger neural responses to negative stimuli and reduced responses to high-arousal stimuli, while those with comorbid depression show blunted responses across brain regions.

Social Anxiety Alters Theory of Mind Activation and Intersubject Neural Variability During Movie Viewing

This study examines how social anxiety affects Theory of Mind activation and neural variability during movie viewing, finding reduced left pSTS activation and distinct neural response patterns in socially anxious individuals.

Aging increases the distinctiveness of emotional brain states across rumination, worry, and positive thinking

This study finds that aging increases the distinctiveness of rumination and worry brain states while reducing anxiety responses, potentially improving emotional well-being.

Social anxiety links of amygdala switch cross puberty

The paper examines how social anxiety relates to amygdala geometry changes during puberty, finding shifts in amygdala volume associations with social anxiety across developmental stages.

Specific amygdala and hippocampal subfield volumes in social anxiety disorder and their relation to clinical characteristics; an international mega-analysis

This study identifies specific amygdala and hippocampal subfield volume differences in social anxiety disorder compared to healthy controls, with associations to comorbid conditions.

Amygdala habituation during exposure is associated with failure to reduce phobic symptoms

This study examines amygdala responses during exposure therapy for spider phobia, finding that increased amygdala activation correlates with better clinical outcomes, supporting the inhibitory learning model over the habituation model.

The unique face of anxious depression: Increased sustained threat circuitry response during fear acquisition

The paper examines fear learning in individuals with major depressive disorder (MDD) and anxiety disorder plus MDD (AD+MDD), finding increased sustained threat circuitry response in AD+MDD during fear acquisition.

The rosy future paradox: Positive future thinking without task relevance enhances negative biases and anxiety for aversive events

This study shows that task-relevant positive future thinking reduces stress and anxiety during a stressful task, while task-irrelevant positive thoughts increase stress reactivity and negative biases.

Attentional bias to threat and gray mater volume morphology in high anxious individuals

The paper examines the relationship between gray matter volume and attentional bias to threat in highly anxious individuals, finding new associations in specific brain regions and suggesting sex-specific contributions.

Reward Prediction Error Signaling during Reinforcement Learning in Social Anxiety Disorder is altered by Social Observation

This study examines how prediction error signaling during reinforcement learning in social anxiety disorder (SAD) is altered by social observation, finding increased DMPFC coupling to prediction errors and reduced ventral pallidum connectivity in SAD.

Facial Emotions Perceptions In Young Female Students With High-Level Anxiety And Subclinical Panic Disorder. ERP And Behavioral Study

This study examines facial emotion processing in young female students with panic disorder using ERP and behavioral measures, finding increased reactivity to threatening facial stimuli and altered neural processing patterns.

Metanalysis of genome-wide association studies for panic disorder suggest pathways and mechanisms of pathogenesis

This study performs a meta-analysis of genome-wide association studies for panic disorder, identifying 25 SNPs and 20 causal genes involved in immune, inflammatory, and developmental pathways.

Dorsomedial prefrontal cortex activity during reinforcement learning discriminates response to Cognitive Behavioural Therapy in depression.

This study identifies dorsomedial prefrontal cortex activity patterns during reinforcement learning that predict response to computerised CBT in depression.