Sleep and Wakefulness Research

Sleep spindle refractoriness segregates periods of memory reactivation

The paper shows that sleep spindles create a refractory period that segments sleep into periods allowing and blocking memory reactivation.

Coupling of autonomic and central events during sleep benefits declarative memory consolidation

The paper identifies coordinated autonomic and central events during NREM sleep that predict declarative memory consolidation.

Identification of Memory Reactivation during Sleep by EEG Classification

This paper develops a machine learning method to detect memory reactivation during sleep using EEG data and finds it is more effective in slow wave sleep than stage 2.

Memory consolidation is linked to spindle-mediated information processing during sleep

The paper shows that memory cues during sleep increase fast spindles and SO up states, which are linked to memory retention and decoding of memory categories.

Heterogeneous origins of human sleep spindles in different cortical layers

This study identifies two distinct patterns of human sleep spindle generation in different cortical layers using microelectrode recordings and factor analysis.

Alpha Oscillations Prior to Encoding Preferentially Modulate Memory Consolidation during Wake Relative to Sleep

The paper investigates how pre-encoding alpha oscillations affect memory consolidation during wake versus sleep, finding that higher alpha power during wake enhances memory retention.

Hypocretin underlies the evolution of sleep loss in the Mexican cavefish

The paper identifies increased Hypocretin/Orexin signaling as a genetic basis for sleep loss in Mexican cavefish compared to surface fish.

Enhanced food-related responses in the ventral medial prefrontal cortex in orexin-deficient narcolepsy patients

This study finds that orexin-deficient narcolepsy patients show enhanced ventral medial prefrontal cortex responses to food words, which predicts increased snack intake.

Replay of large-scale spatio-temporal patterns from waking during subsequent slow-wave sleep in human cortex

The paper identifies replay of waking cortical activity patterns during slow-wave sleep in humans and links them to sleep features like spindles and sharp-wave ripples, supporting memory consolidation theories.

Reactivating vocabularies in the elderly

This study investigates whether memory reactivation during sleep remains effective in older adults, finding that while some benefit from targeted memory reactivation, others do not, with differences linked to sleep efficiency and oscillatory activity patterns.

Sleep Benefits Memory For Semantic Category Structure While Preserving Exemplar-Specific Information

This study shows sleep enhances memory for shared category properties while preserving unique exemplar information, with effects influenced by REM and non-REM sleep.

Cueing memory during sleep is optimal during slow-oscillatory up-states

This study shows that memory cues presented during slow oscillatory up-states during sleep improve recall, while cues during down-states do not.

Individual differences in frequency and topography of slow and fast sleep spindles

This study characterizes individual variability in slow and fast sleep spindle frequency and topography using EEG recordings and introduces a method to reliably separate spindle components across sleep stages.

Role of somatostatin-positive cortical interneurons in the generation of sleep slow waves

This study shows that somatostatin-positive cortical interneurons drive sleep slow waves by triggering neuronal OFF periods during NREM sleep.

Conserved properties of Drosophila Insomniac link sleep regulation and synaptic function

This study shows that Drosophila Insomniac and its mammalian orthologs are functionally conserved in sleep regulation and synaptic function through an evolutionarily conserved ubiquitination pathway.

Sleep-Dependent Modulation Of Metabolic Rate In Drosophila

This paper develops a system to measure sleep and metabolic rate in Drosophila, revealing sleep-dependent regulation of metabolic rate and its genetic basis in starvation.

Neural Correlates of human cognitive abilities during sleep

The paper identifies neural activation patterns during sleep spindles correlated with reasoning abilities using EEG-fMRI.

Low activity microstates during sleep

The paper identifies LOW activity states during non-REM sleep in rats, characterized by reduced neural activity and potential restorative function.

The neural correlates of dreaming

The paper identifies a posterior cortical region with low-frequency activity decreases and high-frequency activity correlations with dream content during both NREM and REM sleep.

Sleep regulation of the distribution of cortical firing rates

This paper explores how sleep, specifically NREM slow oscillations, regulates the distribution of cortical firing rates to support both memory consolidation and neuronal system maintenance.