Advanced Neuroimaging Techniques and Applications

Multimodal anatomical mapping of subcortical regions in Marmoset monkeys using high-resolution MRI and matched histology with multiple stains.

This paper maps subcortical regions in marmoset monkeys using high-resolution MRI and histology, revealing previously invisible structures and providing a 3D atlas for brain research.

Mapping the Macrostructure and Microstructure of the in vivo Human Hippocampus using Diffusion MRI

This paper uses diffusion MRI and computational methods to map macro- and microstructural features of the human hippocampus, revealing distinct subfield characteristics and potential fiber pathway orientations.

Evidence for adaptive myelination of subcortical shortcuts for visual motion perception in healthy adults

The paper reconstructs subcortical visual pathways in humans and finds that the LGN-MT pathway is more heavily myelinated, suggesting faster signal transmission.

Free-water volume fraction increases non-linearly with age in the white matter of the healthy human brain

This study shows that free-water volume fraction in white matter increases non-linearly with age, particularly after 60, with region-specific variations and reduced variability when using FW-compensated MR signals.

RELIEF: a structured multivariate approach for removal of latent inter-scanner effects

RELIEF removes inter-scanner biases in neuroimaging data by using multivariate factorization, improving data integration and statistical power.

Variational Autoencoders for Generating Synthetic Tractography-Based Bundle Templates in a Low-Data Setting

This study uses a variational autoencoder to generate synthetic tractography-based bundle templates from a small dataset, showing improved shape capture compared to standard atlases.

Along-Tract Statistical Mapping of Microstructural Abnormalities in Bipolar Disorder: A Pilot Study

This study uses diffusion MRI and BUAN to map microstructural differences in white matter tracts between bipolar disorder patients and controls, finding altered Fractional Anisotropy in specific pathways.

The spatial extent of anatomical connections within the thalamus varies across the cortical hierarchy in humans and macaques

The study quantifies corticothalamic connectivity patterns in humans and macaques, revealing distinct spatial extents associated with sensorimotor and associative cortical areas.

The BigMac dataset: an open resource combining multi-contrast MRI and microscopy in the macaque brain

The paper introduces the BigMac dataset, combining multi-contrast MRI and microscopy data from a macaque brain, enabling multimodal analysis across scales and tissue states.

Sustaining wakefulness: Brainstem connectivity in human consciousness

The paper maps brainstem connections sustaining wakefulness using ex vivo diffusion MRI, immunohistochemistry, and in vivo 7 Tesla functional MRI.

Hub architecture of the human structural connectome: Links to aging and processing speed

The paper examines how aging affects structural brain hubs using fiber bundle capacity, finding that hub connections are more vulnerable to age-related declines in processing speed.

Delineation of the Trigeminal-Lateral Parabrachial-Central Amygdala Tract in Humans: An Ultra-High Field Diffusion MRI Study

This study identifies the human trigeminal-latPB-CeA circuit using diffusion MRI, showing stronger connectivity to the central amygdala than the basolateral amygdala.

Differentiation of white matter histopathology using b-tensor encoding and machine learning

This study uses b-tensor encoding and machine learning to classify histopathological damage in white matter, showing sensitivity to microstructural features.

Investigating individual variability in microstructural-functional coupling in the human cortex

The paper examines individual variability in microstructural-functional coupling in the human cortex using MRI data and identifies coupling patterns linked to cognitive performance.

High Angular Resolution Susceptibility Imaging and Estimation of Fiber Orientation Distribution Functions in Primate Brain

This paper introduces HARSI, a new method for estimating fiber orientation distribution functions in fixed primate brains, showing it can capture complex fiber configurations comparable to HARDI.

Brain-wide associations between white matter and agehighlight the role of fornix microstructure in brain age

The paper analyzes white matter aging using diffusion MRI data from UK Biobank, finding that fornix microstructure is central to brain age prediction.

Predicting the Distribution of Serotonergic Axons: A Supercomputing Simulation of Reflected Fractional Brownian Motion in a 3D-Mouse Brain Model

The paper uses a supercomputing simulation of fractional Brownian motion to predict serotonergic axon distribution in a 3D mouse brain model, showing qualitative similarity to actual densities.

Using light and X-ray scattering to untangle complex neuronal orientations and validate diffusion MRI

The paper combines scattered light and X-ray imaging with diffusion MRI to accurately map neuronal orientations and validate fiber crossings in human and vervet monkey brains.

Distance-dependent distribution thresholding in probabilistic tractography

This paper introduces a distance-dependent thresholding method for probabilistic tractography to address systematic thresholding across different track lengths and studies.

Susceptibility-induced internal gradients reveal axon morphology and cause anisotropic effects in the dMRI signal

The paper shows that internal magnetic gradients affect diffusion MRI signals in myelinated axons, revealing morphology-dependent anisotropy previously unseen in 2D models.

The influence of axonal beading and undulation on axonal diameter mapping

This study quantifies how axonal beading and undulation affect axon diameter estimation in diffusion MRI, showing potential biases up to 100% in pathological conditions.

How Does White Matter Registration Affect Tractography Alignment?

This work evaluates how white matter registration methods affect tractogram alignment using homologous fiber structures as a benchmark.

High-frequency longitudinal white matter diffusion- & myelin-based MRI database: reliability and variability

The paper evaluates the reliability and variability of diffusion- and myelin-based MRI measurements across multiple sessions and fiber populations, finding moderate to high reliability for diffusion measures and bundle-dependent variability.

Reproducible Tract Profiles (RTP2): from diffusion MRI acquisition to clinical practice and research

The paper introduces RTP2, a reproducible and automated method for white-matter tractography and tractometry using diffusion MRI data.

Structural and functional connectivity reconstruction with CATO - A Connectivity Analysis TOolbox

CATO reconstructs structural and functional brain connectivity from MRI data using diffusion weighted imaging and resting-state fMRI, offering customizable analysis pipelines and open-source tools.

Super-resolution mapping of anisotropic tissue structure with diffusion MRI and deep learning

This paper develops a deep learning method to enhance the spatial resolution of diffusion MRI data, achieving better results than spline interpolation on Human Connectome Project data.

Spatiotemporal tissue maturation of thalamocortical pathways in the human fetal brain

This study uses diffusion MRI to track thalamocortical pathway maturation in human fetal brains, identifying key neurobiological changes in the second to third trimester.

White matter microstructure is associated with the precision of visual working memory

The paper investigates the relationship between white matter microstructure and visual working memory precision using diffusion MRI and mixture distribution modeling.

Sex differences, asymmetry and age-related white matter development in infants and 5-year-olds as assessed with Tract-Based Spatial Statistics

The paper uses tract-based spatial statistics to examine sex differences, lateralization, and age-related white matter development in infants and 5-year-olds using diffusion tensor imaging.

In search of a unifying theory of white matter aging: improving the understanding of tract-wise degeneration using multi-parametric signatures of morphometry and microstructure

This study examines age-related changes in white matter tracts using morphometry and microstructural metrics to identify sex-specific degeneration patterns and propose a unified model of WM aging.