Advanced Neuroimaging Techniques and Applications

A Novel Framework for In-vivo Diffusion Tensor Distribution MRI of the Human Brain

This paper introduces a new framework for in-vivo diffusion tensor distribution MRI of the human brain, enabling detailed microstructural analysis and improved tractography.

Optic radiations representing different eccentricities age differently

The study examines age-related changes in white matter properties of optic radiations carrying foveal, macular, and peripheral visual field information using diffusion MRI data from the UK Biobank.

High spatial overlap but diverging age-related trajectories of cortical MRI markers aiming to represent intracortical myelin and microstructure

The paper examines age-related trajectories of MRI cortical markers and finds high spatial overlap but divergent age trends, suggesting different microstructural origins for these markers.

Real-time tractography-assisted neuronavigation for TMS

This paper develops a real-time tractography-assisted TMS neuronavigation system and demonstrates its feasibility through comparison with offline tractography results.

Learning Optimal White Matter Tract Representations from Tractography using a Deep Generative Model for Population Analyses

This paper uses a ConvVAE to reduce the dimensionality of white matter tractography data, identifies 6 tracts with significant differences between Alzheimer's patients and controls, and preserves distances in a 6-dimensional space.

Human white matter myelination rate slows down at birth

The paper finds that myelin growth slows after birth, particularly in preterm infants, and links this delay to long-term developmental consequences.

Incremental improvements in tractometry-based brain-age modeling with deep learning

This study evaluates deep learning improvements for brain-age modeling using diffusion MRI data in children and adolescents, finding small but notable gains with recurrent neural networks.

Characterization of early white matter changes in CADASIL using microscopic diffusion imaging and relaxometry

This study uses diffusion MRI and relaxometry to identify microstructural changes in white matter of CADASIL mice, finding increased extracellular free water and reduced myelin content.

Establishing the Validity of Compressed Sensing Diffusion Spectrum Imaging

This study evaluates six compressed sensing diffusion spectrum imaging (CS-DSI) schemes, finding they provide accurate and reliable white matter structure measures with up to 80% reduced scan time compared to full DSI.

Genetic architecture of the white matter connectome of the human brain

The paper identifies 355 genomic loci associated with white matter connectivity in the human brain, linking them to neurodevelopmental processes and polygenic risk for brain disorders.

A Role for the Fornix in Temporal Sequence Memory

This study investigates the role of the fornix in sequence memory by correlating its microstructure with memory performance in healthy adults.

High resolution quantitative and functional MRI indicate lower myelination of thin and thick stripes in human secondary visual cortex

This study uses high-resolution MRI to show that thin and thick stripes in human V2 have lower myelination compared to surrounding gray matter.

Region-specific impact of aging on cortical myelination and thickness

The paper examines aging effects on cortical thickness and myelin concentration using MRI data from a large cohort, finding complex regional patterns and MTR as a more reliable myelin proxy.

Specific and non-linear effects of glaucoma on optic radiation tissue properties

This study uses diffusion MRI and a CNN to show glaucoma has a unique non-linear effect on optic radiation tissue properties, unlike linear effects on other brain connections.

A Structural Connectivity Atlas of Limbic Brainstem Nuclei

The paper maps the structural connectivity of five brainstem nuclei to limbic cortical regions using MRI and tractography, creating a freely available atlas for future research.

High-Resolution Magnetization-Transfer Imaging of Post-Mortem Marmoset Brain: Comparisons with Relaxometry and Histology

The paper measures magnetization-transfer (MT) and relaxometry parameters in fixed marmoset brain tissue and compares them with histology to assess their correlation with myelin and iron content.

Identifying the midline thalamus in humans in vivo

This paper introduces a method to identify the midline thalamus in humans using diffusion imaging and clustering, showing reliable classification of midline thalamic clusters in two datasets.

Robust associations between white matter microstructure and general intelligence

The paper identifies white matter regions consistently associated with general intelligence across four independent samples using tract-based spatial statistics.

Short superficial white matter and aging: a longitudinal multi-site study of 1,293 subjects and 2,711 sessions

The paper analyzes longitudinal MRI data from 1,293 subjects to study age-related changes in superficial white matter microstructure and U-fiber volume and length.

BundleCleaner: Unsupervised Denoising and Subsampling of Diffusion MRI-Derived Tractography Data

BundleCleaner denoises and subsamples diffusion MRI tractography data, improving alignment with atlas bundles and enabling efficient tractometry analysis in Alzheimer's disease studies.

ReTrace: Topological evaluation of white matter tractography algorithms using Reeb graphs

ReTrace evaluates tractography algorithms using Reeb graphs, showing no single algorithm consistently outperforms others and deterministic methods better capture fiber bundle properties.

Meningioma microstructure assessed by diffusion MRI: an investigation of the source of mean diffusivity and fractional anisotropy by quantitative histology

This paper investigates how histological features like cell density and structure anisotropy explain variations in diffusion MRI metrics MD and FAIP in meningioma tumors, finding that cell density explains variability across but not within tumors.

The Human Brain Connectome Weighted by the Myelin Content and Total Intra-Axonal Cross-Sectional Area of White Matter Tracts

The paper characterizes weighted structural brain networks using white matter microstructural features to improve structure-function models.

Can hubs of the human connectome be identified consistently with diffusion MRI?

This study evaluates how different diffusion MRI processing pipelines affect the identification of connectome hubs in humans, finding significant variability in hub location and connectivity based on processing choices.

Quantitative measures of topographic and divergent/convergent connectivity in diffusion MRI of the human cerebral cortex

The paper quantifies topographic and divergence/convergence connectivity in human cerebral cortex using dMRI data, revealing spatial organization related to cytoarchitecture and functional efficiency.

Fiber-Specific Structural Properties Relate to Reading Skills in Children and Adolescents

The paper investigates the relationship between fiber-specific white matter microstructure and reading skills in children and adolescents, finding a positive association between FDC and reading proficiency.

Single-subject EEG measurement of interhemispheric transfer-time for the in-vivo estimation of axonal morphology

This paper estimates axonal morphology from individual interhemispheric transfer time (IHTT) measurements obtained from single-subject EEG data, showing consistency with histological values but needing improved repeatability.

A Unified Filtering Method for Estimating Asymmetric Orientation Distribution Functions: Where and How Asymmetry Occurs in the Brain

This paper introduces a unified filtering method for estimating asymmetric ODFs in dMRI, showing it can detect complex asymmetric fiber configurations in brain data.

Macromolecular tissue volume mapping of lateral geniculate nucleus subdivisions in living human brains

This paper develops a method to non-invasively identify LGN subdivisions in living humans using MRI and validates it against histological and functional data.

Early structural connectivity within the sensorimotor network: deviations related to prematurity and association to neurodevelopmental outcome

This study examines microstructural differences in sensorimotor white matter tracts in preterm infants compared to full-term infants and links these differences to neurodevelopmental outcomes.