Animal Virus Infections Studies

The golden Syrian hamster (Mesocricetus auratus) as a model to decipher relevant pathogenic aspects of sheep-associated malignant catarrhal fever

This study re-establishes the golden Syrian hamster as an MCF model and identifies T cells and macrophages as key infected cells, with broader viral tropism including endothelial cells and epithelia.

Insect-specific Alphamesonivirus-1 (Mesoniviridae) in lymph node and lung tissues from two horses with acute respiratory syndrome

This paper reports the first detection of Alphamesonivirus-1 in mammals, specifically horses with acute respiratory syndrome, challenging the belief that mesoniviruses are insect-specific.

PRRSV-2 variant classification: a dynamic nomenclature for enhanced monitoring and surveillance

This paper introduces a dynamic classification system for PRRSV-2 genetic variants using clustering algorithms and demonstrates its effectiveness in tracking genetic diversity over time.

Ambisense transcription uncovers hidden coding capacity in compact circular RNA satellite viruses

The paper demonstrates that ambisense transcription allows compact circular RNA viruses to expand coding capacity by expressing additional genes, using kolmioviruses as a case study.

Ambecovirus, a novel Betacoronavirus subgenus circulating in neotropical bats sheds new light on bat-borne coronaviruses evolution

The paper identifies a new Betacoronavirus subgenus, Ambecovirus, in Neotropical bats, revealing its phylogenetic position and potential for interspecies transmission.

Oral and faecal viromes of New Zealand calves on pasture with an idiopathic ill-thrift syndrome

The paper analyzes oral and faecal viromes of New Zealand calves with idiopathic ill-thrift syndrome, finding no novel viruses significantly linked to the syndrome but identifying diverse viral communities.

Diverse Viral Pathogens in Australian Canines: Limited Geographic Structure and the First Detection of an RNA Virus in Dingoes

This study identifies 86 viruses in Australian dogs and dingoes, revealing limited geographic structure and the first detection of rotavirus A in dingoes, suggesting cross-species transmission.

Isolation and molecular characterization of an enteric isolate of the Genotype-I Bovine coronavirus with notable mutations in the receptor binding domain of the spike glycoprotein and deletion downstream the RNA binding domain of the nucleocapsid protein.

This study isolates and characterizes a new BCoV isolate, identifying mutations in the spike protein and deletions in the nucleocapsid gene, with implications for viral pathogenesis and immune evasion.

Identification and genomic characterization of a novel bisegmented coronavirus in the lesser panda

This study identifies and characterizes a novel bisegmented coronavirus, LpCoV, in lesser pandas, proposing it as a new genus within the Coronaviridae family and highlighting its potential zoonotic risk.

Differential prevalence and risk factors for infection with coronaviruses in bats collected during 2020 in Yunnan Province, China

The paper examines CoV prevalence in bats from Yunnan Province, identifying new SARSr-CoVs and factors influencing their distribution and zoonotic risk.

Efficacy of a new multivalent vaccine for the control of bovine respiratory disease (BRD) in commercial fattening units

This study demonstrates that the multivalent vaccine DIVENCE(R) reduces BRD morbidity and antibiotic use in cattle during fattening.

Reassortant strains of infectious bursal disease virus (IBDV) belonging to genogroup A3B1 predominate in British broiler chicken flocks.

The study sequenced IBDV strains from British broiler farms and found reassortant A3B1 strains predominated, often co-infected with A1B1 strains, and showed genetic diversity.

The Ex Vivo Infection of the Peripheral Bovine Mononuclear Cells (PBMCs) and the Bovine Spleen Cells with the Bovine Coronavirus (BCoV) Induced a Differential Expression of the Host Cytokine Genes Profiles and Modulates the Virus Replication

This study infects bovine PBMCs and spleen cells with BCoV, showing differential cytokine gene expression and effects on T-cell populations that may support virus replication.

Detection and full genome sequencing of a Deltacoronavirus and other bird associated viruses from feces of the kelp gull (Larus dominicanus) sampled at the South Shetland Islands Antarctica.

The paper detects a deltacoronavirus in kelp gull fecal samples from Antarctica and sequences its full genome, revealing its classification and potential cross-species transmission.

A genus-specific nsp12 region impacts polymerase assembly in Alpha- and Gammacoronaviruses

The paper compares structural differences in the nsp12 region across Coronavirinae genera, revealing genus-specific impacts on polymerase assembly in Alpha- and Gammacoronaviruses.

Genetic diversity and cross-species transmissibility of bat-associated picornaviruses from Spain

The paper identifies new picornaviruses from Spanish bats, including a potential plant host calhevirus, highlighting their geographic distribution and interspecies transmissibility.

Phylogenetic-based methods for fine-scale classification of PRRSV-2 ORF5 sequences: a comparison of their robustness and reproducibility

This study compares phylogenetic-based methods for fine-scale classification of PRRSV-2 ORF5 sequences, identifying robust approaches that improve resolution over RFLP-typing.

One-pot Golden Gate Assembly of an avian infectious bronchitis virus reverse-genetics system

This paper develops a Golden Gate Assembly-based reverse genetics system for avian infectious bronchitis virus to enable rapid generation of mutants and gene replacements.

Full genome sequencing of dozens of new DNA viruses found in Spanish bat faeces

The paper uses viral metagenomics to analyze bat fecal samples, identifying 50 complete or near-complete DNA virus genomes, including 28 potential new species, expanding the known European DNA virus diversity.

Df-1 Cell Adaptation and Immune Responses of Lc-75 Vaccinal Strain of Infectious Bursal Disease Virus in Chicken

The study evaluates the adaptation of the LC-75 IBDV vaccine strain in DF-1 cells and its immune responses in chickens, finding it immunogenic and less immunosuppressive.

The dual actions of the host miRNA-16a in restricting Bovine coronavirus (BCoV) replication through targeting host cell Furin and in enhancing the host immune response.

This study identifies miRNA-16a as a host factor that inhibits BCoV replication by targeting Furin and enhances immune response, suggesting its potential as an antiviral therapy.

First report of astroviruses in Tanzanian bats

The paper reports the first detection of astroviruses in Tanzanian bats using PCR and phylogenetic analysis.

Longitudinal Survey of Astrovirus infection in different bat species in Zimbabwe: Evidence of high genetic Astrovirus diversity

The paper surveys Astrovirus infection in Zimbabwean bat species, finding high genetic diversity and co-infection with Coronaviruses.

Genetic diversity of domestic cat hepadnavirus in Taiwan

The paper investigates the prevalence of domestic cat hepadnavirus (DCH) in Taiwan, finding 11.27% infection rate and identifying a distinct viral lineage through whole genome sequencing.

Intra-host variation in the spike S1/S2 region of a feline coronavirus type-1 in a cat with persistent infection

The paper tracks intra-host variation in the spike S1/S2 region of FCoV-1 in a cat over six years, showing distinct variants in different tissues and shedding patterns.

Identification of a novel HKU4-related coronavirus in single-cell datasets and clade viral host analysis

The paper identifies a novel HKU4-related coronavirus in pangolin single-cell datasets and investigates its phylogenetic clade and potential contamination sources.

Rapid genotyping of porcine reproductive and respiratory syndrome virus (PRRSV) using MinION nanopore sequencing

This paper develops and optimizes MinION nanopore sequencing methods for rapid genotyping of PRRSV, achieving high sequence identity and coverage in clinical samples.

Identification and genetic characterization of MERS-related coronavirus isolated from Nathusius' pipistrelle (Pipistrellus nathusii) near Zvenigorod (Moscow region, Russia)

The paper identifies and genetically characterizes a novel MERS-related coronavirus from bats, suggesting potential for hedgehogs to act as intermediate hosts.

A universal, single primer amplification protocol (R-SPA) to perform whole genome sequencing of segmented dsRNA reoviruses

This paper introduces a single-primer amplification protocol (R-SPA) for whole genome sequencing of reoviruses, enabling full genome recovery from segmented dsRNA isolates.

Porcine cytomegalovirus detection by nanopore-based metagenomic sequencing in a Hungarian pig farm

The paper uses nanopore sequencing to detect porcine cytomegalovirus in nasal swabs from a Hungarian pig farm.